Cubs vs. White Sox Betting Lines, Odds, & Player Matchups May 17, 2025

Data Skrive
Data Skrive

The Chicago Cubs (25-19) host the Chicago White Sox (14-30) on Saturday in game 1 of a three-game series, with the first pitch at 2:20 p.m. ET from Wrigley Field. The favored Cubs (-267) enter the matchup after a series win over the Marlins, and the underdog White Sox (+217) are coming off of a series win over the Reds. The Cubs’ Matthew Boyd gets the start against the White Sox’s Sean Burke.

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Betting Odds

Cubs to win vs White Sox -267

Bet $20, Payout $27.49

Cubs vs. White Sox betting lines

  • Favorite: Cubs (-267)
  • Underdog: White Sox (+217)
  • Over/under: 10.5

Cubs betting info, hitting leaders, & pitching

Cubs betting info

  • The Cubs have won 64% of the games this season when they were the moneyline favorite (16-9).
  • The Cubs have not yet played as a moneyline favorite of -267 or shorter.
  • Based on this contest’s moneyline, the Cubs have an implied win probability of 72.8%.
  • The Cubs have played in 44 games with a set over/under, and have combined with their opponents to go over the total 26 times (26-16-2).
  • The Cubs have gone 22-22-0 ATS this season.

Cubs hitting info

  • Kyle Tucker is hitting .263 with nine doubles, three triples, 10 home runs and 30 walks.
  • Among all hitters in MLB play, Tucker’s home run total ranks 15th and his RBI tally ranks seventh.
  • Pete Crow-Armstrong has shown off his power as he paces his team with 11 home runs.
  • Crow-Armstrong ranks eighth in home runs among hitters in MLB and 16th in RBI.
  • Crow-Armstrong enters this game on a two-game hitting streak. In his last five games he is batting .263 with two home runs, a walk and three RBIs.
  • Seiya Suzuki paces the Cubs with 11 home runs and 35 runs batted in.
  • Carson Kelly is batting .289 with two doubles, a triple, eight home runs and 20 walks.

Cubs pitching rankings

  • The Cubs pitching staff is 20th in the majors with a collective 8.1 strikeouts per nine innings.
  • The Cubs’ 4.02 team ERA ranks 18th among all league pitching staffs.
  • The Cubs have the 18th-ranked WHIP in baseball (1.302).
  • The Cubs surrender the 20th-fewest home runs in baseball (52 total, 1.2 per game).
  • In their 3-1 loss last time out they struck out 11 Marlins batters while allowing six hits.

White Sox betting info, hitting leaders, & pitching

White Sox betting info

  • The White Sox have been underdogs in 44 games this season and won 14 (31.8%) of those contests.
  • The White Sox have a record of 1-4 when they’re set as the underdog by +217 or more by bookmakers this season.
  • Sportsbooks have implied with the moneyline set for this matchup that the White Sox have a 31.5% chance to win.
  • The White Sox and their opponents have hit the over in 18 of their 44 games with a total this season.
  • The White Sox are 24-20-0 against the spread in their 44 chances this season.

White Sox hitting info

  • Miguel Vargas has been key for Chicago with three home runs, 16 RBI and a batting average of .221 this season.
  • Vargas is 164th in home runs and 136th in RBI among all hitters in the big leagues.
  • Luis Robert’s five home runs are most among Chicago batters. He’s driven in 17 runs this season while slugging .314.
  • Robert is 95th in home runs and 122nd in RBI among all major league hitters this year.
  • Lenyn Sosa’s batting average of .267 leads all Chicago hitters this season.
  • Andrew Vaughn leads Chicago in home runs (five) and runs batted in (18) this season while batting .189.

White Sox pitching rankings

  • The White Sox have a 7.5 K/9 this season as a pitching staff, which ranks 27th in baseball.
  • The White Sox have pitched to a 4.05 ERA this season, which ranks 20th in baseball.
  • The White Sox have a combined WHIP of 1.378 as a pitching staff, which ranks 23rd in MLB.
  • With 48 homers allowed, the White Sox rank 16th in the league at preventing long balls.
  • The White Sox suffered a 7-1 defeat in their most recent game, striking out five Reds batters while allowing 12 hits.
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Betting Guide

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How to Bet Odds

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If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …