The UConn Huskies (5-2) and the Rice Owls (3-4) square off at Rice Stadium on Saturday, October 25, 2025.

The Huskies are double-digit favorites (currently -10.5) in their game against the Owls, with the over/under at 48.5 points. (In terms of the moneyline, the Huskies are -391 and the Owls are +307.)

Read on for our betting preview for this this contest between the Huskies and the Owls, and uncover all of our expert picks here, too!

UConn vs. Rice betting lines

• Spread favorite: Huskies (-10.5)
• Moneyline: Huskies (-391), Owls (+307)
• Total: 48.5 points

UConn vs. Rice betting info and stats

UConn has three wins against the spread in seven opportunities so far this season (3-2-2). UConn has covered the spread one time this season when a favorite of at least 10.5 points. UConn has won five of its six games played when favored on the moneyline this season. Rice has three wins against the spread this season (3-4-0). When Rice is the underdog by 10.5 points or more, it has covered the spread one time (1-1 ATS). In the four games this year, Rice has been moneyline underdogs, it is 1-3.

UConn vs. Rice recent stats and trends

UConn Huskies

• UConn is 2-0-1 against the spread in its past three games, and has a 3-0 straight-up record in those matchups.
• Twice in those three games, the final combined score has gone over the set total.
• UConn’s last three outings have ended with an average of 54.0 points scored. That’s 5.5 more points than this contest’s over/under.

Rice Owls

• Rice is 1-2 against the spread and 3-0 overall over its last three contests.
• One time in those three games, the final combined score exceeded the set total.
• Rice’s last three outings have ended with an average of 49.7 points scored. That’s 1.2 more points than this contest’s over/under.

UConn vs. Rice key players

UConn Huskies

• Joe Fagnano has thrown for 1,918 yards (274.0 ypg) to lead UConn, completing 68.1% of his passes and tossing 15 touchdown passes this season. He’s also figured in the ground game with 94 rushing yards on 27 carries with two rushing touchdowns.
• Cam Edwards has 694 rushing yards on 113 carries with seven touchdowns.
• This season, Jayden Brown has carried the ball 16 times for 159 yards (53.0 per game) and one touchdown.
• Skyler Bell’s 687 yards as a receiver lead the team. He’s been targeted 82 times and has collected 58 catches and seven touchdowns.
• John Neider has put together a 254-yard season so far with one touchdown, hauling in 14 passes on 18 targets.
• Reymello Murphy has a total of 219 receiving yards so far this year, grabbing 17 throws and scoring three touchdowns.
• Bryun Parham, the team’s tackle and sacks leader, has collected 8.5 sacks, 7.0 TFL and 54 tackles.
• Cam Chadwick leads the team with one interception, while also recording 34 tackles and two passes defended.

Rice Owls

• Chase Jenkins has compiled 553 yards on 67.4% passing while recording four touchdown passes with one interception this season. He’s also rushed for 275 yards with four scores.
• Quinton Jackson is his team’s leading rusher with 96 carries for 487 yards, or 69.6 per game. He’s found the end zone three times on the ground, as well.
• Daelen Alexander has totaled 370 yards on 63 carries with three touchdowns.
• Drayden Dickmann has totaled 24 catches this season and his team-high yardage total sits at 262 (37.4 yards per game). He’s been targeted 38 times and has three touchdowns.
• Aaron Turner has 21 receptions (on 28 targets) for a total of 136 yards (19.4 yards per game) this year.
• Tyson Thompson has racked up 66 reciving yards (11.0 ypg) and one touchdown this season.
• Michael Daley has 4.5 sacks to lead the team, and also has 4.0 TFL and eight tackles.
• Andrew Awe, Rice’s leading tackler, has 35 tackles, 2.0 TFL, and 0.5 sacks this year.
• Plae Wyatt has picked off a team-high one pass. He also has six tackles, 1.0 TFL, and one pass defended to his name.