Astros vs. Blue Jays Betting Lines, Odds, & Player Matchups April 21, 2025

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Data Skrive

The Houston Astros (10-11) are looking for Jeremy Pena to extend an 11-game hitting streak when they match up against the Toronto Blue Jays (12-10) on Monday at 8:10 p.m. ET at Daikin Park. The Astros are favored (-139) over the Blue Jays (+118). Hunter Brown starts for Houston, and Kevin Gausman is Toronto’s pick to start.

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Betting Odds

Astros to win vs Blue Jays -139

Bet $20, Payout $34.39

Astros vs. Blue Jays betting lines

  • Favorite: Astros (-139)
  • Underdog: Blue Jays (+118)
  • Over/under: 7.5

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have won 46.2% of the games this season when they were the moneyline favorite (6-7).
  • Houston has gone 3-3 (winning 50% of its games) when it has played as moneyline favorites of -139 or shorter.
  • The Astros have an implied moneyline win probability of 58.2% in this matchup.
  • Houston has played in 21 games with an over/under set, and have combined with its opponents to go over the total eight times (8-11-2).
  • The Astros have covered 52.4% of their games this season, going 11-10-0 ATS.

Astros hitting info

  • Pena has hit a team-best three homers.
  • Pena’s home runs rank 72nd in MLB and he ranks 155th in RBI in MLB.
  • Pena takes an 11-game hitting streak into this game. In his last 10 outings he is batting .297 with three doubles, a home run, four walks and five RBI.
  • Jose Carlos Altuve’s three home runs pace his team.
  • Among all MLB hitters, Altuve ranks 72nd in home runs and 155th in RBI.
  • Isaac Paredes paces the Astros in home runs (three) and runs batted in (11).
  • Jake Meyers’ .305 batting average paces his team.

Astros pitching rankings

  • The 9.5 strikeouts per nine innings put together by the Astros pitching staff ranks seventh in MLB.
  • Houston’s 3.63 team ERA ranks ninth among all MLB pitching staffs.
  • The Astros have the seventh-lowest WHIP in baseball (1.158).
  • The Astros give up the eighth-fewest home runs in baseball (20 total, one per game).
  • Houston struck out four Padres batters while allowing 10 hits in a 3-2 loss in its last game.

Blue Jays betting info, hitting leaders, & pitching

Blue Jays betting info

  • This season, the Blue Jays have won seven out of the 15 games, or 46.7%, in which they’ve been the underdog.
  • Toronto has played as an underdog of +118 or more twice this season and split those games.
  • The bookmakers’ moneyline implies a 45.9% chance of a victory for the Blue Jays.
  • Toronto and its opponents have hit the over in nine of its 22 games with a total this season.
  • The Blue Jays are 16-6-0 ATS in their 22 games with a spread this season.

Blue Jays hitting info

  • Bo Joseph Bichette leads Toronto in runs batted in with 13 and has a batting average of .313.
  • Among all hitters in the majors, Bichette’s home run total is 268th, and his RBI total is 38th.
  • Bichette brings a five-game hitting streak into this game. In his last five games he is batting .364 with three doubles, a walk and three RBI.
  • Vladimir Guerrero Jr. has collected 25 hits this season and has an OBP of .408. He’s slugging .415 on the year.
  • Guerrero is 169th overall in homers and 84th in RBI this year.
  • Guerrero has hit safely in two straight games. In his last five games he is hitting .400 with two doubles, a home run, eight walks and three RBI.
  • Andres Gimenez leads Toronto in home runs with three. He’s driven in eight runs and is slugging .361.
  • George Springer leads Toronto with a batting average of .344. He’s also hit two home runs with 11 RBI.

Blue Jays pitching rankings

  • The Blue Jays have a 9.6 K/9 this season as a pitching staff, fifth-best in baseball.
  • Toronto has the eighth-best ERA (3.59) in the majors this season.
  • The Blue Jays have a combined 1.113 WHIP as a pitching staff, fourth-lowest in MLB.
  • The Blue Jays have allowed the second-most home runs this season with 31, or 1.4 per game.
  • Last time out, Toronto fell to the Mariners 8-3. Its pitchers compiled 18 strikeouts and 12 hits allowed.
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