Tigers vs. Guardians Betting Lines, Odds, & Player Matchups May 23, 2025

Data Skrive
Data Skrive

The Cleveland Guardians (26-22) will look to Carlos Santana, who is riding a two-game home run streak, when they play the Detroit Tigers (33-17). The Tigers are favored on the moneyline (-136) for this matchup with the Guardians (+115), which starts at 7:10 p.m. ET on Friday at Comerica Park. Detroit’s Jackson Jobe starts against Cleveland’s Slade Cecconi.

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Odds to Win

Tigers to win vs Guardians -136

Bet $20, Payout $34.71

Tigers vs. Guardians betting lines

  • Favorite: Tigers (-136)
  • Underdog: Guardians (+115)
  • Over/under: 8.5

Tigers betting info, hitting leaders, & pitching

Tigers betting info

  • The Tigers have a 22-7 record in games they were listed as the moneyline favorite (winning 75.9% of those games).
  • When playing as moneyline favorites with odds of -136 or shorter, Detroit has a record of 19-4 (82.6%).
  • The Tigers have an implied moneyline win probability of 57.6% in this contest.
  • Detroit has played in 50 games with set over/under, and have combined with opponents to go over the total 25 times (25-21-4).
  • The Tigers have put together a 28-22-0 record against the spread this season (covering 56% of the time).

Tigers hitting info

  • Spencer Torkelson leads the Tigers in home runs (12) and runs batted in (39).
  • Among all hitters in MLB action, Torkelson’s home run total ranks ninth and his RBI tally ranks fourth.
  • Riley Greene’s 12 home runs and .287 batting average both lead his team.
  • Greene ranks ninth in homers and 14th in RBI this year.
  • Greene enters this game on a four-game hitting streak. During his last five outings he is batting .368 with two doubles, a home run, two walks and four RBIs.
  • Gleyber Torres has six doubles, five home runs and 16 walks while hitting .281.
  • Kerry Carpenter is hitting .278 with six doubles, a triple, 10 home runs and six walks.

Tigers pitching rankings

  • The 8.8 strikeouts per nine innings put together by the Tigers pitching staff ranks ninth in the majors.
  • Detroit’s 3.33 team ERA ranks fifth among all MLB pitching staffs.
  • Tigers pitchers combine for the No. 6 WHIP in MLB (1.175).
  • The Tigers surrender the 15th-fewest home runs in baseball (53 total, 1.1 per game).
  • Detroit defeated the Cardinals 5-1 in its last game with nine strikeouts while allowing five hits.

Guardians betting info, hitting leaders, & pitching

Guardians betting info

  • The Guardians have been underdogs in 27 games this season and won 13 (48.1%) of those contests.
  • Cleveland has a record of 4-6, a 40% win rate, when it’s set as an underdog of +115 or more by sportsbooks this season.
  • Bookmakers have implied with the moneyline set for this matchup that the Guardians have a 46.5% chance to win.
  • So far this season, Cleveland and its opponents have hit the over in 20 of its 46 games with a total.
  • The Guardians are 20-26-0 ATS in their 46 games with a spread this season.

Guardians hitting info

  • Jose Ramirez is batting .304 with nine home runs and 24 RBI for Cleveland this season.
  • Among all hitters in MLB, Ramirez’s home run total is 35th, and his RBI total is 74th.
  • Ramirez heads into this game on a 14-game hitting streak. In his last 10 outings he is batting .395 with three doubles, three home runs, four walks and six RBIs.
  • Steven Kwan is batting .317 to lead Cleveland, while adding four homers and 17 runs batted in this season.
  • Kwan is 149th among hitters in the big leagues in home runs, and 153rd in RBI.
  • Kwan has hit safely in two straight games. During his last five outings he is hitting .250 with two doubles and a walk.
  • Santana has 37 hits this season and a slash line of .231/.337/.363.
  • Santana takes a three-game hitting streak into this game. During his last five outings he is batting .316 with two home runs, two walks and five RBIs.
  • Kyle Manzardo leads Cleveland in home runs (10) and runs batted in (26) this season while batting .216.

Guardians pitching rankings

  • The Guardians strike out 8.7 batters per nine innings as a pitching staff, 10th-best in MLB.
  • Cleveland has pitched to a 4.12 ERA this season, which ranks 19th in baseball.
  • The Guardians have a combined WHIP of 1.408 as a pitching staff, which ranks 24th in MLB.
  • The Guardians have given up the 15th-fewest long balls so far this season with 53 home runs allowed.
  • Last time out, Cleveland defeated the Twins, 5-1, with seven strikeouts and three hits allowed.
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