Astros vs. Mariners Betting Lines, Odds, & Player Matchups May 23, 2025

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Data Skrive

The Houston Astros (26-24) play the Seattle Mariners (28-21) after Jose Altuve homered twice in a 9-2 win over the Mariners. The Astros are favored (-125) in this matchup with the Mariners (+106), which begins at 8:10 p.m. ET on Friday. Ryan Gusto starts for Houston while Seattle will counter with Emerson Hancock.

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Odds to Win

Astros to win vs Mariners -125

Bet $20, Payout $36.00

Astros vs. Mariners betting lines

  • Favorite: Astros (-125)
  • Underdog: Mariners (+106)
  • Over/under: 8.5

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have gone 18-15 in games they were favored on the moneyline (winning 54.5% of those games).
  • In games it has played as moneyline favorites with odds of -125 or shorter, Houston has a record of 12-10 (54.5%).
  • Based on this matchup’s moneyline, the Astros’ implied win probability is 55.6%.
  • Houston has combined with opponents to hit the over on the total 21 times this season for a 21-27-2 record against the over/under.
  • The Astros have put together a 27-23-0 record ATS this season (covering 54% of the time).

Astros hitting info

  • Isaac Paredes leads the Astros in home runs (10) and runs batted in (29).
  • Among all hitters in MLB action, Paredes’ home run total ranks 21st and his RBI tally ranks 32nd.
  • Jeremy Pena is batting .298 with eight doubles, a triple, six home runs and 13 walks.
  • Pena ranks 87th in home runs among hitters in MLB and 67th in RBI.
  • Jake Meyers leads the Astros with a team-high batting average of .304.
  • Meyers has safely hit in seven straight games. In his last 10 outings he is hitting .324 with a double, a home run, three walks and two RBIs.
  • Altuve is hitting .243 with six doubles, six home runs and 15 walks.

Astros pitching rankings

  • The pitching staff for the Astros has a collective 9.5 K/9, the third-best in the majors.
  • Houston has the eighth-ranked team ERA across all MLB pitching staffs (3.46).
  • The Astros have the third-lowest WHIP in MLB (1.148).
  • Astros pitchers combine to give up the ninth-fewest home runs in baseball (47 total, 0.9 per game).
  • Houston struck out 15 Mariners batters while giving up 10 hits in a 9-2 win in its last game.

Mariners betting info, hitting leaders, & pitching

Mariners betting info

  • This season, the Mariners have won 11 out of the 19 games, or 57.9%, in which they’ve been the underdog.
  • This season, Seattle has won seven of its 11 games, or 63.6%, when it’s the underdog by at least +106 on the moneyline.
  • Oddsmakers have implied with the moneyline set for this matchup that the Mariners have a 48.5% chance to win.
  • Games involving Seattle have gone over the total set by sportsbooks in 27 of 49 chances this season.
  • The Mariners are 24-25-0 ATS in their 49 games with a spread this season.

Mariners hitting info

  • Cal Raleigh leads Seattle in home runs (16) and runs batted in (33) this season while batting .253.
  • In all of Major League Baseball, Raleigh is third in homers and 19th in RBI.
  • Raleigh has safely hit in three games in a row. In his last five games he is batting .250 with two doubles, a home run, two walks and two RBIs.
  • Julio Rodriguez has 45 hits and an OBP of .309 to go with a slugging percentage of .415 this season.
  • Rodriguez currently ranks 35th in home runs and 42nd in RBI in the big leagues.
  • Jorge Polanco has 37 hits this season and a slash line of .291/.345/.575.
  • J.P. Crawford leads Seattle with a batting average of .262. He’s also hit four home runs with 19 RBI.

Mariners pitching rankings

  • The Mariners strike out 8.2 batters per nine innings as a pitching staff, 18th in MLB.
  • Seattle has the 13th-ranked ERA (3.85) in the majors this season.
  • Mariners pitchers have a 1.312 WHIP this season, 19th in the majors.
  • With just 49 homers allowed, the Mariners rank 10th in the league at preventing long balls.
  • Last time out, Seattle fell to the Astros 9-2. Its pitchers compiled six strikeouts and 13 hits allowed.
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Ryan Knuppel

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About Ryan Knuppel

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