Padres vs. Giants Betting Lines, Odds, & Player Matchups June 5, 2025

Data Skrive
Data Skrive

Manny Machado leads the San Diego Padres (35-24) into a contest against the San Francisco Giants (33-28) a game after he totaled four hits in a 3-2 win over the Giants. The Padres are favored (-115) against the Giants (-104) in this outing, which begins at 3:45 p.m. ET on Thursday. San Diego has Dylan Cease set to start, and San Francisco will send out Robbie Ray.

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Money Line

Padres to win vs Giants -115

Bet $20, Payout $37.39

Padres vs. Giants betting lines

  • Favorite: Padres (-115)
  • Underdog: Giants (-104)
  • Over/under: 7

Padres betting info, hitting leaders, & pitching

Padres betting info

  • The Padres have a 21-13 record in games they were listed as the moneyline favorite (winning 61.8% of those games).
  • When playing as moneyline favorites with odds of -115 or shorter, San Diego has a record of 20-12 (62.5%).
  • The implied moneyline probablility for this matchup gives the Padres a 53.5% chance to win.
  • San Diego has played in 59 games with set over/under, and have combined with opponents to go over the total 24 times (24-33-2).
  • The Padres have put together a 32-27-0 record against the spread this season.

Padres hitting info

  • Fernando Tatis Jr. has racked up a team-best 13 home runs.
  • Among batters in baseball, Tatis ranks 15th in homers and 80th in RBI.
  • Tatis takes a two-game hitting streak into this matchup. In his last five games he is hitting .176 with four walks.
  • Machado’s .315 batting average is a team-high mark.
  • Among all MLB hitters, Machado ranks 92nd in home runs and 73rd in RBI.
  • Luis Arraez has 12 doubles, three triples, three home runs and 11 walks while batting .283.
  • Gavin Sheets has racked up 34 runs batted in to pace his team.

Padres pitching rankings

  • The Padres pitching staff is eighth in MLB with a collective 8.9 strikeouts per nine innings.
  • San Diego’s 3.53 team ERA ranks eighth across all MLB pitching staffs.
  • Padres pitchers combine for the No. 9 WHIP in the majors (1.203).
  • Padres pitchers combine to give up the 12th-fewest home runs in baseball (61 total, 1.0 per game).
  • In its 3-2 win last time out, San Diego struck out four Giants batters while allowing six hits.

Giants betting info, hitting leaders, & pitching

Giants betting info

  • This season, the Giants have won 11 out of the 23 games, or 47.8%, in which they’ve been the underdog.
  • This season, San Francisco has won nine of its 18 games, or 50%, when it’s the underdog by at least -104 on the moneyline.
  • The implied probability of a win by the Giants, based on the moneyline, is 51%.
  • San Francisco’s games have gone over the total in 27 of its 61 chances.
  • The Giants are 27-34-0 against the spread in their 61 chances this season.

Giants hitting info

  • Jung Hoo Lee has been key for San Francisco with 63 hits, an OBP of .316 plus a slugging percentage of .423.
  • Among all hitters in MLB, Lee’s home run total is 116th, and his RBI total is 59th.
  • Heliot Ramos leads San Francisco in batting average (.293) and home runs (11) this season, while also driving in 31 runs.
  • Ramos currently is 32nd in homers and 59th in RBI in the major leagues.
  • Ramos has safely hit in seven games in a row. In his last 10 outings he is hitting .279 with a triple, two home runs, three walks and five RBIs.
  • Wilmer Flores is among the top hitters for San Francisco with a .253 average, 10 homers and 47 RBI.
  • Flores heads into this matchup on a three-game hitting streak. In his last five games he is hitting .211 with two RBIs.
  • Matt Chapman has 50 hits and an OBP of .357 to go with a slugging percentage of .425 this season.
  • Chapman heads into this game on a two-game hitting streak. During his last five outings he is batting .375 with a double, a home run, four walks and an RBI.

Giants pitching rankings

  • The Giants average 8.9 strikeouts per nine innings as a pitching staff, eighth-most in the majors.
  • San Francisco has pitched to a 3.07 ERA this season, which ranks second in baseball.
  • The Giants have a combined WHIP of just 1.202 as a pitching staff, which is the eighth-best in baseball this season.
  • The Giants have given up the fewest long balls so far this season with only 41 home runs allowed.
  • Last time out, San Francisco fell to the Padres 3-2. Its pitchers compiled eight strikeouts and 10 hits allowed.
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Betting Guide

How Money Line Works?

Moneyline betting is by far the easiest way to place a sports wager. There are no point spreads to parse, no garbage-time free throws to ruin your betting day, and no last-minute meaningless touchdowns to take you from a winner to a loser.

How to Bet Odds

When we, as sports fans, learned our multiplication tables, we aced the number 7. Seven, 14, 21, 28, 35, 42 were easy because we all watched football on the weekends. Multiplication by sevens, then add a three, a six after a missed PAT.

How to Bet on NFL Games

Baseball is America’s pastime, but football is America’s crazed passion, with its weekly schedule of games, millions of television viewers across the country and the world, and the billion-dollar stadiums that serve as Sunday cathedrals in 32 American cities.

What is the Spread?

If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …