Cubs vs. Cardinals Betting Lines, Odds, & Player Matchups August 8, 2025

Data Skrive
Data Skrive

The Chicago Cubs (66-48) and the St. Louis Cardinals (58-58) square off in the first of a three-game series on Friday at Busch Stadium, starting at 8:15 p.m. ET. The favored Cubs (-159) are coming off of a 1-2 series loss to the Reds, and the underdog Cardinals (+133) head into the matchup after a 2-1 series win over the Dodgers. Chicago’s Matthew Boyd and St. Louis’ Michael McGreevy will start this matchup.

Check out all the Latest Baseball Betting Previews!

Money Line

Cubs to win vs Cardinals -159

Bet $20, Payout $32.58

Cubs vs. Cardinals betting lines

  • Favorite: Cubs (-159)
  • Underdog: Cardinals (+133)
  • Over/under: 8.5

Cubs betting info, hitting leaders, & pitching

Cubs betting info

  • The Cubs have been the moneyline favorite 80 total times this season. They’ve gone 53-27 in those games.
  • When playing as moneyline favorites with odds of -159 or shorter, Chicago has a 25-11 record (winning 69.4% of its games).
  • Based on this matchup’s moneyline, the Cubs’ implied win probability is 61.4%.
  • Chicago has combined with opponents to go over the total 57 times this season for a 57-52-5 record against the over/under.
  • The Cubs have put together a 55-59-0 record ATS this season.

Cubs hitting info

  • Kyle Tucker has 21 doubles, four triples, 18 home runs and 75 walks while batting .271.
  • Tucker ranks 48th in homers and 48th in RBI among all hitters in MLB.
  • Pete Crow-Armstrong has hit 27 home runs to pace his team.
  • Among all MLB hitters, Crow-Armstrong ranks seventh in homers and ninth in RBI.
  • Seiya Suzuki leads the Cubs with 27 home runs and 84 runs batted in.
  • Nico Hoerner has a club-best .292 batting average.

Cubs pitching rankings

  • The pitching staff for the Cubs has a collective 7.6 K/9, the third-worst in the majors.
  • Chicago’s 3.90 team ERA ranks 16th across all MLB pitching staffs.
  • Cubs pitchers combine for the No. 5 WHIP in baseball (1.216).
  • Cubs pitchers combine to surrender 144 total home runs at a clip of 1.3 per game (23rd-fewest in baseball).
  • Chicago took down the Reds 6-1 in its last game with 12 strikeouts while allowing four hits.

Cardinals betting info, hitting leaders, & pitching

Cardinals betting info

  • The Cardinals have won 30, or 49.2%, of the 61 games they’ve played as underdogs this season.
  • St. Louis has a record of 7-13, a 35% win rate, when it’s set as an underdog of +133 or more by bookmakers this season.
  • The implied probability of a win by the Cardinals, based on the moneyline, is 42.9%.
  • St. Louis and its opponents have hit the over in 58 of its 115 games with a total this season.
  • The Cardinals are 61-54-0 against the spread this season.

Cardinals hitting info

  • Brendan Donovan leads St. Louis with a batting average of .280. He’s also hit nine home runs with 43 RBI.
  • Among all hitters in MLB, Donovan is 167th in home runs and 133rd in RBI.
  • Alec Burleson is batting .279 with an OBP of .333 and a slugging percentage of .450 this season.
  • Burleson is 93rd in homers and 83rd in RBI among all MLB batters this year.
  • Willson Contreras leads St. Louis in home runs with 16 and runs batted in with 64.
  • Contreras brings a two-game hitting streak into this game. In his last five games he is hitting .294 with a double, two home runs, two walks and three RBIs.
  • Masyn Winn has 106 hits and an OBP of .325 to go with a slugging percentage of .392 this season.

Cardinals pitching rankings

  • The Cardinals strike out just 7.4 batters per nine innings as a pitching staff, which ranks 29th in MLB.
  • St. Louis pitchers have a combined ERA of 4.22 ERA this year, which ranks 20th in MLB.
  • Cardinals pitchers have a 1.288 WHIP this season, 17th in the majors.
  • The Cardinals have allowed the fifth-fewest home runs this season at just 113, or 1.0 per game.
  • Last time out, St. Louis defeated the Dodgers, 5-3, with six strikeouts and eight hits allowed.
Author Profile
BetDecider Team

The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.

Ryan Knuppel

Knup Solutions [molongui_author_name]

About Ryan Knuppel

Ryan has been one of the leading sports business & iGaming professionals for over 15 years. He started as a freelance writer and now operates one of the top sports content agencies around, Knup Solutions. He has literally written 10,000 plus sports and betting related articles across the web.

 

Sports Network:

sports20.com, usawager.com, knupsports.com, baseballspotlight.com, basketballarticles.com, betdecider.com, njsportsbookreview.com, dunkelindex.com, sportspub.com, oddschoice.com

 

Betting Guide

How Money Line Works?

Moneyline betting is by far the easiest way to place a sports wager. There are no point spreads to parse, no garbage-time free throws to ruin your betting day, and no last-minute meaningless touchdowns to take you from a winner to a loser.

How to Bet Odds

When we, as sports fans, learned our multiplication tables, we aced the number 7. Seven, 14, 21, 28, 35, 42 were easy because we all watched football on the weekends. Multiplication by sevens, then add a three, a six after a missed PAT.

How to Bet on NFL Games

Baseball is America’s pastime, but football is America’s crazed passion, with its weekly schedule of games, millions of television viewers across the country and the world, and the billion-dollar stadiums that serve as Sunday cathedrals in 32 American cities.

What is the Spread?

If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …