The Wyoming Cowboys (1-0) face an FCS opponent, the Northern Iowa Panthers (1-0), on Saturday, September 6, 2025 at Jonah Field at War Memorial Stadium.

The Panthers are expected to lose by at least two scores (currently +13.5) versus the Cowboys (with an over/under of 47.5 points).

Read on for our preview for this this matchup between the Cowboys and the Panthers, and discover all of our betting picks here, too!

Wyoming vs. Northern Iowa betting lines

• Spread favorite: Cowboys (-13.5)
• Moneyline: Cowboys (-529), Panthers (+395)
• Total: 47.5 points
• TV Channel: Altitude Sports Overflow
• Live Stream: Fubo

Wyoming vs. Northern Iowa betting info and stats

Wyoming has been perfect against the spread (1-0-0) this season. In one game as the moneyline favorite, Wyoming won. Northern Iowa is undefeated against the spread (1-0-0) this season. Northern Iowa has not played as an underdog on the moneyline so far this season.

Wyoming vs. Northern Iowa key players

Wyoming Cowboys

• Last year Evan Svoboda produced 1,308 passing yards (130.8 per game), a 49.1% completion percentage, five touchdowns, and eight interceptions. He also added 237 rushing yards on 109 carries with five rushing TDs (averaging 21.5 rushing yards per game).
• Sam Scott picked up 435 rushing yards (48.3 per game) and three touchdowns last season.
• Harrison Waylee ran for 323 yards on 63 carries (35.9 yards per game), with one rushing touchdown last year.
• Jaylen Sargent reeled in 23 catches for 480 yards (40.0 per game) while being targeted 42 times. He also scored two touchdowns.
• John Michael Gyllenborg produced last year, grabbing 30 passes for 425 yards and three touchdowns. He collected 38.6 receiving yards per game.
• Chris Durr Jr. reeled in 31 passes on 46 targets for 348 yards and one touchdown, compiling 29.0 receiving yards per game.
• Last season Tyce Westland stacked up 3.5 sacks, 3.0 TFL and 30 tackles.
• Shae Suiaunoa was a wrecking ball on the field, collecting 75 tackles, 8.0 TFL, and one sack last year.
• Last season Wrook Brown had a huge stat line of three interceptions, 39 tackles and four passes defended.

Northern Iowa Panthers

• Matthew Schecklman threw for 1,276 yards and seven touchdowns last season.
• Tye Edwards compiled 1,022 rushing yards and six touchdowns on the ground during last year’s campaign.
• Amauri Pesek-Hickson rushed for 455 yards and four touchdowns last season. He also averaged 17.7 receiving yards per game.
• Sergio Morancy was targeted 3.8 times per game and collected 543 receiving yards and seven touchdowns over the course of 2024.
• Desmond Hutson collected two touchdowns and had 466 receiving yards (42.4 ypg) in 2024.
• Layne Pryor averaged 22.0 receiving yards per game on 3.1 targets per game a season ago.
• Last year Zach Mehmert accumulated 2.0 sacks, 39 tackles and four passes defended.
• Tucker Langenberg put together an excellent stat line last year, accruing 15 tackles and one interception.