UConn vs. DePaul betting: College basketball preview for Dec. 21

Data Skrive
Data Skrive

The No. 5 UConn Huskies (11-1, 1-0 Big East) are big, 14.5-point favorites as they look to continue a seven-game winning streak when they visit the DePaul Blue Demons (8-4, 0-1 Big East) on Sunday, December 21, 2025 at Wintrust Arena. The contest airs at 4:30 p.m. ET on Fox Sports 1. The point total in the matchup is set at 136.5.

Check out all the Latest NCAA Basketball Betting Previews!

Spread

UConn Cover -14.5 vs DePaul -110

Bet $20, Payout $38.18

UConn vs. DePaul betting lines

  • UConn moneyline odds to win: -1449
  • DePaul moneyline odds to win: +837
  • Spread: UConn (-14.5)
  • Total: 136.5

UConn statistics, trends and more

As the away team

  • At home last season, UConn sported a worse record against the spread (7-9-0) compared to its ATS record in road games (6-5-0).
  • The Huskies eclipsed the total less consistently at home last season, hitting the over in six of 16 home matchups (37.5%). In road games, they hit the over in six of 11 games (54.5%).
  • As a moneyline favorite last year, UConn took 14 of 16 games at home, good for a .875 winning percentage. UConn won four of five games away from home (.800) as a moneyline favorite.

Last season stats

  • The Huskies were 90th in the nation in points scored (77.0 per game) and 56th in points conceded (68.0) last year.
  • Last year, UConn was 111th in the country in rebounds (33.1 per game) and second-best in rebounds conceded (25.9).
  • Last season the Huskies were eighth-best in college basketball in assists with 17.3 per game.

UConn betting records this season

  • ATS Record: 4-8-0 (Home: 2-6-0; Away: 1-0-0)
  • ATS Record When Favored by 14.5+: 2-4-0 (As Favorite: 4-8-0; As Underdog: 0-0-0)
  • O-U-P: 4-8-0 (Home: 2-6-0; Away: 0-1-0)
  • Record When Moneyline Favorite: 8-1 (Home: 4-1; Away: 1-0)
  • Record When Moneyline Underdog: 0-0 (Home: 0-0; Away: 0-0)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
49.7 (33rd in nation) 37.2 (eighth) 33.5 (167th) 27.7 (45th) 18.4 (26th) 9.4 (23rd)

Need to know more about sports betting before you put down a wager on UConn vs. DePaul? Here’s everything you need to know about how to bet.

DePaul statistics, trends and more

As the home team

  • DePaul performed better against the spread at home (10-9-0) than away (5-7-0) last season.
  • In terms of the over/under, Blue Demons games went over 11 of 19 times at home (57.9%) and seven of 12 on the road (58.3%) last year.
  • The Blue Demons, when moneyline underdogs, won a lower percentage of games at home (1-7) than away (2-10) last year.

Last season stats

  • Offensively, the Blue Demons scored 72.4 points per game (218th-ranked in college basketball) last season. They ceded 74.5 points per contest on defense (251st-ranked).
  • Last season DePaul grabbed 31.4 rebounds per game (207th-ranked in college basketball) and gave up 32.3 rebounds per contest (257th-ranked).
  • The Blue Demons ranked 61st in the country with 15.4 assists per game.

DePaul betting records this season

  • ATS Record: 7-5-0 (Home: 4-4-0; Away: 2-0-0)
  • ATS Record When Underdog by 14.5+: 1-0-0 (As Favorite: 4-4-0; As Underdog: 3-1-0)
  • O-U-P: 4-8-0 (Home: 3-5-0; Away: 0-2-0)
  • Record When Moneyline Favorite: 7-1 (Home: 6-1; Away: 0-0)
  • Record When Moneyline Underdog: 1-3 (Home: 0-1; Away: 1-1)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
45.2 (204th in nation) 42.4 (131st) 31.1 (276th) 30.8 (171st) 16.9 (63rd) 11.2 (144th)
Author Profile
BetDecider Team

The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.

Ryan Knuppel

Knup Solutions [molongui_author_name]

About Ryan Knuppel

Ryan has been one of the leading sports business & iGaming professionals for over 15 years. He started as a freelance writer and now operates one of the top sports content agencies around, Knup Solutions. He has literally written 10,000 plus sports and betting related articles across the web.

 

Sports Network:

sports20.com, usawager.com, knupsports.com, baseballspotlight.com, basketballarticles.com, betdecider.com, njsportsbookreview.com, dunkelindex.com, sportspub.com, oddschoice.com

 

Betting Guide

How Money Line Works?

Moneyline betting is by far the easiest way to place a sports wager. There are no point spreads to parse, no garbage-time free throws to ruin your betting day, and no last-minute meaningless touchdowns to take you from a winner to a loser.

How to Bet Odds

When we, as sports fans, learned our multiplication tables, we aced the number 7. Seven, 14, 21, 28, 35, 42 were easy because we all watched football on the weekends. Multiplication by sevens, then add a three, a six after a missed PAT.

How to Bet on NFL Games

Baseball is America’s pastime, but football is America’s crazed passion, with its weekly schedule of games, millions of television viewers across the country and the world, and the billion-dollar stadiums that serve as Sunday cathedrals in 32 American cities.

What is the Spread?

If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …