Cardinals vs. Padres Betting Lines, Odds, & Player Matchups June 15, 2026

Data Skrive

The St. Louis Cardinals (38-31) play the San Diego Padres (37-33) a game after Ivan Herrera homered twice in a 9-6 win over the Twins. The Cardinals are favored (-147) in this matchup with the Padres (+123), which starts at 7:45 p.m. ET on Monday. St. Louis has Dustin May starting, and San Diego counters with Lucas Giolito.

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Odds to Win

Cardinals to win vs Padres -147

Bet $20, Payout $33.61

Cardinals vs. Padres betting lines

  • Favorite: Cardinals (-147)
  • Underdog: Padres (+123)
  • Over/under: 8.5

Cardinals betting info, hitting leaders, & pitching

Cardinals betting info

  • The Cardinals have been the moneyline favorite 14 total times this season. They’ve gone 10-4 in those games.
  • St. Louis has played as moneyline favorites of -147 or shorter in just one game this season, which it won.
  • The implied moneyline probablility in this matchup gives the Cardinals a 59.5% chance to win.
  • St. Louis has had an over/under set by bookmakers 69 times, and have combined with opponents to go over the total in 28 of those games (28-34-7).
  • The Cardinals have gone 43-26-0 against the spread this season.

Cardinals hitting info

  • Jordan Walker leads the Cardinals in home runs (18), runs batted in (56) and has racked up a team-best batting average of .294.
  • Among batters in MLB, Walker ranks ninth in homers and first in RBI.
  • Alec Burleson is batting .287 with 17 doubles, 13 home runs and 26 walks.
  • Burleson currently ranks 35th in homers and seventh in RBI in the bigs.
  • Burleson has safely hit in 14 games in a row. In his last 10 outings he is batting .310 with three doubles, six home runs, four walks and 12 RBIs.
  • Herrera is hitting .267 with 13 doubles, a triple, nine home runs and 41 walks.
  • JJ Wetherholt is hitting .255 with seven doubles, 10 home runs and 32 walks.
  • Wetherholt brings a two-game hitting streak into this game. During his last five outings he is hitting .348 with a home run, a walk and six RBIs.

Cardinals pitching rankings

  • The 7.7 strikeouts per nine innings compiled by the Cardinals pitching staff ranks 27th in MLB.
  • St. Louis’ 4.15 team ERA ranks 16th across all MLB pitching staffs.
  • Pitchers for the Cardinals combine for the 20th-ranked WHIP in baseball (1.346).
  • Cardinals pitchers combine to surrender the 15th-fewest home runs in baseball (77 total, 1.1 per game).
  • St. Louis took down the Twins 9-6 in its last game with eight strikeouts while allowing seven hits.

Padres betting info, hitting leaders, & pitching

Padres betting info

  • The Padres have entered the game as underdogs 36 times this season and won 18, or 50%, of those games.
  • San Diego has entered 10 games this season as the underdog by +123 or more and is 4-6 in those contests.
  • The bookmakers’ moneyline implies a 44.8% chance of a victory for the Padres.
  • San Diego’s games have gone over the total in 31 of its 70 chances.
  • The Padres are 38-32-0 ATS in their 70 games with a spread this season.

Padres hitting info

  • Xander Bogaerts is batting .228 with eight home runs and 27 RBI for San Diego this season.
  • In all of Major League Baseball, Bogaerts is 93rd in homers and 130th in RBI.
  • Gavin Sheets has 47 hits and an OBP of .322 to go with a slugging percentage of .458 this season.
  • Sheets is 51st in homers and 105th in RBI among all MLB hitters this year.
  • Sheets takes a four-game hitting streak into this game. During his last five outings he is hitting .250 with two doubles, a home run, two walks and four RBIs.
  • Fernando Tatis Jr.’s batting average of .282 leads all San Diego hitters this season.
  • Tatis heads into this matchup on a five-game hitting streak. In his last five games he is batting .417 with two doubles, a home run, a walk and five RBIs.
  • Manny Machado leads San Diego in home runs with 12 and runs batted in with 35.

Padres pitching rankings

  • The Padres average the 14th-most strikeouts per nine innings (8.5) in the majors this season.
  • San Diego has pitched to a 3.91 ERA this season, which ranks ninth in baseball.
  • The Padres rank 15th in MLB with a combined 1.289 WHIP this season.
  • The Padres have allowed the seventh-fewest home runs this season at just 71, or 1.0 per game.
  • San Diego earned a 5-2 win in its most recent game, striking out 10 Orioles batters while allowing 10 hits.
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