The Arizona State Sun Devils (7-3) square off against a conference opponent when they visit the Colorado Buffaloes (3-7) on Saturday, November 22, 2025 at Folsom Field in a Big 12 clash.

The Sun Devils are expected to win by at least a touchdown (currently -7) versus the Buffaloes. The over/under for this matchup is 47.5 points.

Keep reading for our betting preview for this this game between the Sun Devils and the Buffaloes, and find all of our expert predictions here, too!

Arizona State vs. Colorado betting lines

• Spread favorite: Sun Devils (-7)
• Moneyline: Sun Devils (-265), Buffaloes (+213)
• Total: 47.5 points
• TV Channel: ESPN2
• Live Stream: Fubo

Arizona State vs. Colorado betting info and stats

Arizona State has four wins against the spread so far this season (4-5-1). Arizona State has covered the spread in one game when the favorite by at least 7 points (a 1-3 ATS record). Arizona State has won four of its six games played as the moneyline favorite this season. Colorado has four wins against the spread this season (4-6-0). When Colorado is an underdog of 7 points or more, it has have yet to cover the spread. This is the ninth time this year Colorado is the moneyline underdog and has gone 1-7 in such contests.

Arizona State vs. Colorado recent stats and trends

Arizona State Sun Devils

• Arizona State is 1-2 against the spread in its past three games, and has a 2-1 straight-up record in those contests.
• The final combined score of the last three Arizona State games surpassed the set total once.
• Arizona State’s last three games have ended with an average of 47.2 points scored. That’s 0.3 fewer points than this contest’s over/under.

Colorado Buffaloes

• Colorado is winless against the spread (0-3) and 2-1 overall in its last three matchups.
• The final combined score of the past three Colorado games has surpassed the set total two times.
• The past three Colorado games averaged 3.8 more points (51.3) than this matchup’s point total.

Arizona State vs. Colorado key players

Arizona State Sun Devils

• Sam Leavitt has 1,628 yards passing for Arizona State, completing 60.7% of his passes and collecting 10 touchdowns and three interceptions this season. He’s also helped out on the ground with 306 rushing yards (43.7 ypg) on 73 carries with five rushing touchdowns.
• The team’s top rusher, Raleek Brown, has carried the ball 151 times for 823 yards (82.3 per game), scoring three times. He’s also caught 32 passes for 196 yards and one touchdown.
• This season, Jeff Sims has carried the ball 75 times for 411 yards (68.5 per game) and two touchdowns.
• Jordyn Tyson has hauled in 57 receptions for 628 yards (89.7 yards per game) to lead the team so far this season. He’s found the end zone eight times as a receiver.
• Chamon Metayer has hauled in 35 receptions totaling 370 yards, finding the end zone four times as a receiver so far this campaign.
• Malik McClain has a total of 296 receiving yards so far this year, grabbing 17 passes.
• Keyshaun Elliott, the team’s tackle and sacks leader, has recorded 5.0 sacks, 10.0 TFL and 76 tackles.
• Martell Hughes has picked off a team-leading two passes. He also has 21 tackles, 1.0 TFL, and two passes defended to his name.

Colorado Buffaloes

• Kaidon Salter has been a dual threat for Colorado this season. He has 1,242 passing yards (155.3 per game) while completing 63.1% of his passes. He’s thrown 10 touchdown passes and six interceptions this season. On the ground, he’s compiled 294 yards (36.8 ypg) on 89 carries with five rushing touchdowns.
• Micah Welch is his team’s leading rusher with 81 carries for 313 yards, or 31.3 per game. He’s found the end zone two times on the ground, as well.
• Omarion Miller’s 652 receiving yards (72.4 yards per game) lead the team. He has 34 receptions on 53 targets with seven touchdowns.
• Joseph Williams has 30 receptions (on 47 targets) for a total of 450 yards (50.0 yards per game) and four touchdowns this year.
• Sincere Brown’s 35 targets have resulted in 18 grabs for 316 yards and two touchdowns.
• Arden Walker has 2.5 sacks to pace the team, and also has 3.0 TFL and 29 tackles.
• Jeremiah Brown is the team’s tackle leader this year. He’s totaled 56 tackles, 6.0 TFL, and two sacks.
• Preston Hodge has picked off a team-high one pass. He also has 33 tackles, 1.0 TFL, and one pass defended to his name.