MAC opponents meet when the Buffalo Bulls (2-3) and the Eastern Michigan Eagles (1-4) square off on Saturday, October 4, 2025 at UB Stadium.

The Bulls are expected to win by at least a touchdown (currently -9.5) versus the Eagles. The over/under for this matchup is 53.5 points.

Keep reading to check out our preview for this this contest between the Bulls and the Eagles, and find all of our betting picks here, too!

Buffalo vs. Eastern Michigan betting lines

• Spread favorite: Bulls (-9.5)
• Moneyline: Bulls (-346), Eagles (+274)
• Total: 53.5 points

Buffalo vs. Eastern Michigan betting info and stats

Buffalo, through five games with a spread this season, is 2-2-1 against the spread. Buffalo has covered the spread one time this season when a favorite of at least 9.5 points. In the three games favored on the moneyline, Buffalo has recorded a 2-1 record. Eastern Michigan has won twice against the spread this season (2-3-0). In the two games Eastern Michigan has been the underdog by at least 9.5 points, it covered the spread once. Eastern Michigan has been an underdog on the moneyline four times this year, going 1-3 in those games.

Buffalo vs. Eastern Michigan recent stats and trends

Buffalo Bulls

• Buffalo is winless against the spread (0-2-1) and 1-2 overall during its last three games.
• Buffalo and its opponents have hit the over once in those games.
• The last three Buffalo games averaged 48.0 total points, 5.5 fewer points than this matchup’s over/under.

Eastern Michigan Eagles

• Eastern Michigan is 2-1 against the spread in its last three games and has a 1-2 straight-up record in those contests.
• The final combined score of the past three Eastern Michigan games has surpassed the set total two times.
• The past three Eastern Michigan games averaged 1.8 fewer points (51.7) than this matchup’s over/under.

Buffalo vs. Eastern Michigan key players

Buffalo Bulls

• Ta’Quan Roberson has compiled 662 yards (165.5 ypg) on 59-of-95 passing with five touchdowns compared to two interceptions this season. In addition, he’s added 165 rushing yards (41.3 ypg) on 31 carries while scoring two touchdowns on the ground.
• Al-Jay Henderson has carried the ball 96 times for a team-high 337 yards (67.4 per game) with four scores. He has also caught 16 passes for 133 yards and one receiving touchdown.
• Lamar Sperling has been handed the ball 29 times this year and racked up 191 yards (47.8 per game) with one touchdown.
• Victor Snow’s 274 yards as a receiver pace the team. He’s been targeted 32 times and has collected 23 catches and three touchdowns.
• Nik McMillan has put up a 157-yard season so far with one touchdown, reeling in 13 passes on 24 targets.
• Khalil Murdock, who paces the team in sacks and tackles, has racked up 2.0 sacks, 3.0 TFL and 43 tackles.
• Mitchell Gonser has picked off a team-high one pass. He also has 18 tackles, 2.0 TFL, one sack, and one pass defended to his name.

Eastern Michigan Eagles

• Noah Kim has racked up 1,168 yards on 63.4% passing while recording five touchdown passes with three interceptions this season. He’s also rushed for 73 yards with three scores.
• Dontae McMillan has run for 416 yards on 62 carries so far this year while scoring one time on the ground. He’s also added 12 catches, totaling 134 yards and one touchdown in the passing game.
• Tavierre Dunlap has piled up 45 carries and totaled 153 yards with three touchdowns while also gaining 64 yards through the air .
• Terry Lockett Jr. paces his team with 263 receiving yards on 19 receptions with one touchdown.
• Joshua Long has caught 15 passes and compiled 186 receiving yards (37.2 per game) with two touchdowns.
• Nick Devereaux’s 12 catches (on 20 targets) have netted him 164 yards (32.8 ypg).
• Quincy Byas leads the team with 1.0 sack, and also has 1.0 TFL and four tackles.
• Bryce Llewellyn has been all over the field, leading the team in both tackles and interceptions. He has 37 tackles, 2.0 TFL, and one interception so far.