The BYU Cougars (3-0) take on a conference opponent when they visit the Colorado Buffaloes (2-2) on Saturday, September 27, 2025 at Folsom Field in a Big 12 showdown.

The Buffaloes are underdogs, but by less than a touchdown (+6.5), versus the Cougars (with an over/under of 49.5 points).

Keep reading to check out our betting primer for this this matchup between the Cougars and the Buffaloes, and discover all of our predictions here, too!

BYU vs. Colorado betting lines

• Spread favorite: Cougars (-6.5)
• Moneyline: Cougars (-242), Buffaloes (+196)
• Total: 49.5 points
• TV Channel: ESPN
• Live Stream: Fubo

BYU vs. Colorado betting info and stats

BYU has an against-the-spread record of 3-0-0 this season. BYU has covered the spread three times when favored by 6.5 or more points this season (3-0 ATS). BYU is 3-0 in the three games this season it has been favored on the moneyline. Colorado, through four games with a set spread this season, is 2-2-0 against the spread. Colorado has been the underdog on the moneyline two times this season, and it lost both games.

BYU vs. Colorado key players

BYU Cougars

• Bear Bachmeier has recorded 518 yards (172.7 ypg) on 42-of-63 passing with four touchdowns compared to zero interceptions this season. In addition, he’s added 65 rushing yards (21.7 ypg) on 22 carries while scoring four touchdowns on the ground.
• LJ Martin has 342 rushing yards on 40 carries with one touchdown.
• Sione I Moa has been handed the ball 17 times this year and racked up 90 yards (30.0 per game) with one touchdown. He’s also helped out in the pass game with five grabs for 34 yards
• Chase Roberts’ leads his squad with 185 yards as a receiver. He’s racked up that yardage on 11 catches (out of 18 targets) and scored one touchdown.
• Carsen Ryan has put together a 146-yard season so far with two touchdowns, hauling in nine passes on 11 targets.
• Parker Kingston’s nine receptions have turned into 67 yards.
• Jack Kelly leads the team with 3.0 sacks, and also has 3.0 TFL and 10 tackles.
• Logan Lutui, BYU’s tackle leader, has 12 tackles and 1.0 TFL this year.
• Evan Johnson has picked off a team-leading two passes. He also has six tackles and two passes defended to his name.

Colorado Buffaloes

• Kaidon Salter has thrown for 565 yards on 48-of-72 passing with four touchdowns and zero interceptions this season. He has chipped on the ground, as well, with 154 yards and three rushing touchdowns.
• Micah Welch has run for 143 yards across 29 attempts, scoring one touchdown.
• Sincere Brown has collected seven catches this season and his team-high yardage total sits at 203 (50.8 yards per game). He’s been targeted 12 times and has two touchdowns.
• Omarion Miller has 10 receptions (on 17 targets) for a total of 181 yards (60.3 yards per game) and one touchdown this year.
• Joseph Williams’ 16 targets have resulted in nine receptions for 164 yards and two touchdowns.
• Keaten Wade leads the team with 1.5 sacks, and also has 3.0 TFL and 12 tackles.
• Reginald Hughes, Colorado’s tackle leader, has 18 tackles this year.
• RJ Johnson leads the team with one interception, while also collecting six tackles and one pass defended.