White Sox vs. Astros Betting Lines, Odds, & Player Matchups July 26, 2026

Data Skrive

The Chicago White Sox (54-49) host the Houston Astros (52-54) for a matchup sportsbooks have listed as a pick ’em, with both teams equal to win on the moneyline. The action starts on Sunday at Rate Field, beginning at 2:10 p.m. ET. Erick Fedde gets the starting nod for Chicago, and Ronel Blanco is Houston’s pick to start.

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Moneyline

White Sox to win vs Astros -111

Bet $20, Payout $38.02

White Sox vs. Astros betting lines

  • Favorite: White Sox (-111)
  • Underdog: Astros (-111)
  • Over/under: 9.5

White Sox betting info, hitting leaders, & pitching

White Sox betting info

  • The White Sox are 14-9 in games they were favored on the moneyline (winning 60.9% of those games).
  • When playing as moneyline favorites with odds of -111 or shorter, Chicago has a 12-9 record (winning 57.1% of its games).
  • The implied moneyline probablility in this matchup gives the White Sox a 52.6% chance to win.
  • Chicago has played in 103 games with an over/under set, and have combined with its opponents to go over the total 59 times (59-43-1).
  • The White Sox have collected a 60-43-0 record ATS this season.

White Sox hitting info

  • Miguel Vargas leads the White Sox with 61 runs batted in.
  • Among hitters in MLB play, Vargas ranks 20th in home runs and 23rd in RBI.
  • Sam Antonacci has a club-high .278 batting average.
  • Antonacci ranks 188th in homers and 193rd in RBI among hitters in MLB action.
  • Colson Montgomery has hit a team-best 24 home runs.
  • Chase Meidroth is batting .276 with 18 doubles, seven home runs and 38 walks.

White Sox pitching rankings

  • The White Sox pitching staff is 14th in the majors with a collective 8.6 strikeouts per nine innings.
  • Chicago’s 4.13 team ERA ranks 11th among all MLB pitching staffs.
  • The White Sox have the 17th-ranked WHIP in MLB (1.311).
  • The White Sox surrender the 10th-fewest home runs in baseball (110 total, 1.1 per game).
  • Chicago struck out nine Astros batters while giving up 13 hits in a 9-5 loss in its last game.

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have been underdogs in 65 games this season and won 34 (52.3%) of those contests.
  • Houston has entered 67 games this season as the underdog by -111 or more and is 35-32 in those contests.
  • The implied probability of a win by the Astros, based on the moneyline, is 52.6%.
  • Houston and its opponents have gone over the total this season in 54 of its 106 opportunities.
  • The Astros are 54-52-0 against the spread this season.

Astros hitting info

  • Yordan Alvarez leads Houston in batting average (.325), home runs (34) and runs batted in (77) this season.
  • Among all batters in MLB, Alvarez ranks first in home runs and second in RBI.
  • Isaac Paredes has 95 hits and an OBP of .356 to go with a slugging percentage of .435 this season.
  • Paredes ranks 76th in homers and 41st in RBI among all MLB hitters this year.
  • Christian Walker is slashing .232/.307/.447 this season for the Astros.
  • Jeremy Pena is batting .315 with an OBP of .371 and a slugging percentage of .477 this season.
  • Pena brings a seven-game hitting streak into this matchup. During his last 10 games he is hitting .410 with three home runs, two walks and seven RBIs.

Astros pitching rankings

  • The Astros strike out 8.9 batters per nine innings as a pitching staff, 10th-best in MLB.
  • Houston has the 25th-ranked ERA (4.67) in the majors this season.
  • The Astros have a combined WHIP of 1.384 as a pitching staff, which ranks 25th in MLB.
  • With 142 homers allowed, the Astros rank 26th in the league at preventing long balls.
  • Houston pitchers struck out eight White Sox batters while allowing eight hits in a 9-5 win last time out.
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Ryan Knuppel

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About Ryan Knuppel

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Betting Guide

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