Christian McCaffrey Player Prop Bets and Odds: 49ers vs. Panthers | November 24, 2025

Data Skrive
Data Skrive

The San Francisco 49ers, led by Christian McCaffrey, will face the Carolina Panthers at 8:15 p.m. ET on Monday for a Week 12 NFL contest. Here is analysis of McCaffrey’s prop bets, stats and trends ahead of this contest to help you pick out your best bets.

Rushing Yards Prop

Christian McCaffrey to go over 70.5 yards

Bet $20, Payout $37.54

Christian McCaffrey Prop Lines

  • Matchup: San Francisco 49ers vs. Carolina Panthers
  • Time: 8:15 p.m. ET
  • Date: November 24, 2025
  • Rushing yards prop: Over 70.5 (-114)
  • Receiving yards prop: Over 48.5 (-114)

Christian McCaffrey Stats and Trends

  • McCaffrey leads the team with 707 rushing yards on 193 attempts (64.3 ypg), and has six rushing TDs.
  • McCaffrey runs for 64.3 yards per game, less than Monday’s prop total (70.5).
  • In three of 11 games (27.3%), McCaffrey has rushed for more than 70.5 yards.
  • His average rushing yards over/under is 68 yards, and he has fallen short by an average of 3.7 yards.
  • In four of 11 opportunities (36.4%), McCaffrey has gone beyond his rushing yards prop bet.
  • He has scored multiple rushing TDs twice this year, and has scored in four games overall.
  • McCaffrey also has caught 74 passes for 732 yards, the most receiving yards on the team while catching five touchdown passes.

Recent Performances vs. the Panthers

Week Opponent Rush Yards Allowed Rush TDs Allowed
1 Jaguars 200 1
2 Cardinals 82 1
3 Falcons 131 0
4 Patriots 104 3
5 Dolphins 19 0
6 Cowboys 31 0
7 Jets 81 0
8 Bills 245 4
9 Packers 104 1
10 Saints 122 0
11 Falcons 125 3

49ers Home Splits

  • At home, the 49ers score 20.8 points per game and give up 23.3. That’s less than they score overall (23.7), but more than they allow (22.9).
  • The 49ers rack up 365.3 yards per game at home (15.9 more than their overall average), and give up 319.5 at home (33.4 less than overall).
  • In home games, the 49ers accumulate 264.3 passing yards per game and give up 208.3. That’s more than they gain overall (254.5), and less than they allow (249.1).
  • The 49ers’ average rushing yards gained (101) and allowed (111.3) at home are both higher than their overall averages of 94.8 and 103.8, respectively.
  • The 49ers’ offensive third-down percentage at home (47.8%) is higher than their overall average (45.7%). And their defensive third-down percentage at home (38.8%) is lower than overall (40.8%).
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