Reds vs. Cardinals Betting Lines, Odds, & Player Matchups May 23, 2026

Data Skrive

The Cincinnati Reds (26-24) and the St. Louis Cardinals (28-21) meet on Saturday at Great American Ball Park, starting at 7:15 p.m. ET. The Reds are favored on the moneyline (-110), while the Cardinals are -109 underdogs, even though they are favored against the spread (1.5) with +145 odds. Chase Petty starts for Cincinnati while St. Louis will counter with Kyle Leahy.

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Betting Odds

Reds to win vs Cardinals -110

Bet $20, Payout $38.18

Reds vs. Cardinals betting lines

  • Favorite: Reds (-110)
  • Underdog: Cardinals (-109)
  • Over/under: 9.5

Reds betting info, hitting leaders, & pitching

Reds betting info

  • The Reds have been favored on the moneyline 16 total times this season. They’ve finished 9-7 in those games.
  • Cincinnati has a 9-7 record (winning 56.2% of its games) when it has played as moneyline favorites of -110 or shorter.
  • The Reds have a 52.4% chance to win this matchup based on the moneyline’s implied probability.
  • In the 50 games in which bookmakers have set an over/under for Cincinnati, it has combined with opponents to go over the total 31 times (31-18-1).
  • The Reds have put together a 30-20-0 record against the spread this season (covering 60% of the time).

Reds hitting info

  • Sal Stewart leads the Reds with 12 home runs and 33 runs batted in.
  • Stewart’s home runs rank 14th in MLB and he ranks 13th in RBI in MLB.
  • Stewart has safely hit in four games in a row. During his last five outings he is hitting .529 with a double, two home runs, four walks and four RBIs.
  • Elly De La Cruz’s .290 batting average is a team-high mark.
  • De La Cruz currently ranks 20th in home runs and 18th in RBI in the bigs.
  • Spencer Steer is hitting .273 with nine doubles, seven home runs and 15 walks.
  • Steer takes an 11-game hitting streak into this game. In his last 10 games he is hitting .349 with three doubles, a home run, three walks and six RBIs.
  • Matt McLain is hitting .202 with nine doubles, five home runs and 24 walks.

Reds pitching rankings

  • The pitching staff for the Reds has a collective 7.9 K/9, which ranks 23rd in MLB.
  • Cincinnati has the 25th-ranked team ERA across all MLB pitching staffs (4.72).
  • The Reds have the third-highest WHIP in MLB (1.460).
  • Reds pitchers combine to give up 68 total home runs at a rate of 1.4 per game (fifth-most in baseball).
  • In its 9-4 win last time out, Cincinnati struck out seven Phillies batters while allowing six hits.

Cardinals betting info, hitting leaders, & pitching

Cardinals betting info

  • This season, the Cardinals have won 24 out of the 41 games, or 58.5%, in which they’ve been the underdog.
  • This season, St. Louis has won 24 of its 41 games, or 58.5%, when it’s the underdog by at least -109 on the moneyline.
  • The oddsmakers’ moneyline implies a 52.2% chance of a victory for the Cardinals.
  • So far this season, St. Louis and its opponents have hit the over in 20 of its 49 games with a total.
  • The Cardinals have an ATS record of 30-19-0 in 49 games with a spread this season.

Cardinals hitting info

  • Jordan Walker leads St. Louis in home runs with 13, runs batted in with 35 and his batting average of .295 is also best on his team.
  • Among all hitters in the majors, Walker is eighth in home runs and 10th in RBI.
  • Alec Burleson is batting .290 with an OBP of .359 and a slugging percentage of .468 this season.
  • Burleson ranks 54th among hitters in the big leagues in home runs, and 11th in RBI.
  • Burleson enters this game on a six-game hitting streak. During his last 10 outings he is hitting .389 with two doubles, a home run, a walk and four RBIs.
  • JJ Wetherholt has collected 44 base hits, an OBP of .357 and a slugging percentage of .413 this season.
  • Ivan Herrera has collected 48 hits this season and has an OBP of .386. He’s slugging .426 on the year.

Cardinals pitching rankings

  • The Cardinals have a 7.3 K/9 this season as a pitching staff, worst in baseball.
  • St. Louis has the 20th-ranked ERA (4.25) in the majors this season.
  • Cardinals pitchers have a 1.386 WHIP this season, 23rd in the majors.
  • The Cardinals have allowed the 14th-fewest home runs this season with 52, or 1.1 per game.
  • St. Louis pitchers struck out nine Pirates hitters while allowing 10 base hits in a 6-2 loss its last time out.
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Betting Guide

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How to Bet Odds

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