The No. 4 Clemson Tigers (0-0) and the No. 9 LSU Tigers (0-0) play at Memorial Stadium (Clemson, SC) on Saturday, August 30, 2025.
The Clemson Tigers are the favorites (-4.5) in their game versus the LSU Tigers, with the over/under being 56.5 points. (On the moneyline, the Clemson Tigers are -204 and the LSU Tigers are +169.)
Keep reading to check out our preview for this this contest between the Tigers and the Tigers, and uncover all of our betting picks here, too!
To Cover the Spread
Bet $20, Payout $38.02
Clemson -4.5 vs. LSU
Clemson vs. LSU betting lines
- Spread favorite: Clemson Tigers (-4.5)
- Moneyline: Clemson Tigers (-204), LSU Tigers (+169)
- Total: 56.5 points
- TV Channel: ESPN U
- Live Stream: Fubo
Clemson vs. LSU betting info and stats
- Clemson was 6-8-0 against the spread last season.
- Clemson went 5-5 as at least 4.5-point favorites last year.
- Clemson had six of its 14 games hit the over last year.
- LSU’s record against the spread last year was 5-8-0.
- Last season, five of LSU’s 13 games hit the over.
Clemson vs. LSU key players
Clemson Tigers
- Cade Klubnik put together an impressive passing stat line last year with 3,639 yards (259.9 yards per game), going 308-for-486 (63.4% completion percentage), 36 touchdowns and six interceptions. He was impressive in the running game as well, with 463 rushing yards on 119 carries, seven rushing TDs, and averaging 33.1 yards per game.
- Phil Mafah racked up 1,125 rushing yards (80.4 per game) and eight touchdowns last season.
- Antonio Williams picked up 74 receptions for 902 yards and 11 touchdowns last season. He was targeted 101 times, and averaged 64.4 yards per game.
- Bryant Wesco Jr. produced last year, catching 41 passes for 708 yards and five touchdowns. He averaged 59.0 receiving yards per game.
- T.J. Moore’s stat line last year: 651 receiving yards, 45 catches, five touchdowns, on 75 targets.
- T.J. Parker’s hard work last season put up a stat line of 11.0 sacks, 11.0 TFL and 55 tackles.
- Barrett Carter was a wrecking ball on the field, collecting 82 tackles, 9.0 TFL, and 3.5 sacks last year.
- Last season Khalil Barnes had a huge stat line of four interceptions, 61 tackles and four passes defended.
LSU Tigers
- Garrett Nussmeier completed 64.1% of his passes to throw for 4,039 yards and 29 touchdowns last season.
- Caden Durham racked up six rushing touchdowns on 58.0 yards per game last season. Durham was also effective in the passing game, totaling 28 catches and two touchdowns over the course of the year.
- Last season Josh Williams rushed for 482 yards and hauled in passes for 263 yards. He also scored six total touchdowns.
- Aaron Anderson averaged 67.3 receiving yards and racked up five receiving touchdowns over the course of the 2024 season.
- Kyren Lacy caught 58 passes last season on his way to 866 yards and nine receiving touchdowns.
- Mason Taylor averaged 45.5 receiving yards per game on 6.9 targets per game a season ago.
- Last year Bradyn Swinson put pressure on opposing quarterbacks with 8.5 sacks, and added 9.0 TFL and 46 tackles.
- Whit Weeks had an impactful defensive performance last season with 66 tackles, 4.0 TFL, 3.5 sacks, and one interception.
- Zy Alexander hauled in two interceptions in addition to 24 tackles, 1.0 TFL, one sack, and two passes defended a year ago.
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BetDecider Team
The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.


