Guardians vs. Astros Betting Lines, Odds, & Player Matchups June 6, 2025

Data Skrive
Data Skrive

The Cleveland Guardians (33-28) host the Houston Astros (34-28) on Friday at Progressive Field, starting at 7:10 p.m. ET. The Guardians are favored on the moneyline (-112), while the Astros are -107 underdogs, despite being favored against the spread (1.5) with +155 odds. Cleveland’s Logan Allen gets the start against Houston’s Colton Gordon.

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Moneyline

Guardians to win vs Astros -112

Bet $20, Payout $37.86

Guardians vs. Astros betting lines

  • Favorite: Guardians (-112)
  • Underdog: Astros (-107)
  • Over/under: 8.5

Guardians betting info, hitting leaders, & pitching

Guardians betting info

  • The Guardians have a 14-8 record in games they were favored on the moneyline (winning 63.6% of those games).
  • When it has played as moneyline favorites with odds of -112 or shorter, Cleveland has a record of 14-7 (66.7%).
  • The Guardians have a 52.8% chance to win this game based on the moneyline’s implied probability.
  • In the 59 games in which bookmakers have set an over/under for Cleveland, it has combined with opponents to go over the total 25 times (25-31-3).
  • The Guardians are 28-31-0 ATS this season.

Guardians hitting info

  • Jose Ramirez leads the Guardians in home runs (11), runs batted in (29) and has accumulated a team-best batting average of .330.
  • In MLB play, Ramirez ranks 33rd in homers and 76th in RBI.
  • Ramirez enters this matchup on a five-game hitting streak. During his last five outings he is batting .450 with a double, two home runs, two walks and two RBIs.
  • Steven Kwan is hitting .306 with 13 doubles, five home runs and 20 walks.
  • Among all MLB hitters, Kwan ranks 151st in homers and 146th in RBI.
  • Carlos Santana leads the Guardians with 29 runs batted in.
  • Santana brings a 14-game hitting streak into this game. In his last 10 outings he is batting .378 with two doubles, a home run, five walks and three RBIs.
  • Kyle Manzardo has hit 11 home runs with 29 RBI. Both lead his team.

Guardians pitching rankings

  • The 8.8 strikeouts per nine innings compiled by the Guardians pitching staff ranks 11th in MLB.
  • Cleveland has a 3.99 team ERA that ranks 18th across all MLB pitching staffs.
  • The Guardians average MLB’s 23rd-ranked WHIP (1.376).
  • Guardians pitchers combine to allow 67 total home runs at a rate of 1.1 per game (17th-fewest in MLB).
  • Cleveland struck out five Yankees batters while giving up 10 hits in a 4-0 loss in its last game.

Astros betting info, hitting leaders, & pitching

Astros betting info

  • The Astros have entered the game as underdogs 20 times this season and won 11, or 55%, of those games.
  • Houston has a record of 10-7, a 58.8% win rate, when it’s set as an underdog of -107 or more by bookmakers this season.
  • The Astros have a 51.7% chance to win this game based on the implied probability of the moneyline.
  • Houston and its opponents have gone over the total this season in 25 of its 62 opportunities.
  • In 62 games with a spread this season, the Astros are 33-29-0 ATS.

Astros hitting info

  • Jeremy Pena leads Houston with a .318 batting average. He’s also hit nine homers and has 31 RBI.
  • Among all hitters in the big leagues, Pena’s home run total is 58th, and his RBI total is 65th.
  • Pena heads into this game on an 11-game hitting streak. In his last 10 outings he is batting .425 with four doubles, three home runs, three walks and six RBIs.
  • Isaac Paredes is batting .252 this season with a team-high 14 home runs and 37 RBI.
  • Paredes currently ranks 12th in home runs and 28th in RBI in the big leagues.
  • Jose Altuve has collected 62 base hits, an OBP of .310 and a slugging percentage of .404 this season.
  • Altuve brings a three-game hitting streak into this game. During his last five outings he is batting .278 with a walk and an RBI.
  • Jake Meyers is batting .287 with an OBP of .345 and a slugging percentage of .399 this season.

Astros pitching rankings

  • The Astros have a 9.8 K/9 this season as a pitching staff, first-best in baseball.
  • Houston has pitched to a 3.57 ERA this season, which ranks ninth in baseball.
  • The Astros have a combined WHIP of just 1.161 as a pitching staff, which is the third-best in baseball this season.
  • The Astros have given up the eighth-fewest long balls so far this season with only 59 home runs allowed.
  • Last time out, Houston defeated the Pirates, 8-2, with 16 strikeouts and five hits allowed.
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Betting Guide

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