Creighton vs. DePaul betting: College basketball preview for Feb. 25

Data Skrive

The Creighton Bluejays (14-14, 8-9 Big East) are at home in Big East action against the DePaul Blue Demons (14-13, 6-10 Big East) on Wednesday, February 25, 2026 at 9 p.m. ET. The Bluejays are 3.5-point favorites in the game. The matchup has an over/under of 142.5.

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Creighton Cover -3.5 vs DePaul -121

Bet $20, Payout $36.53

Creighton vs. DePaul betting lines

  • Creighton moneyline odds to win: -201
  • DePaul moneyline odds to win: +162
  • Spread: Creighton (-3.5)
  • Total: 142.5

Creighton statistics, trends and more

As the home team

  • Creighton has done a better job covering the spread on the road (4-7-0) than it has at home (4-10-0).
  • The Bluejays have eclipsed the total in a higher percentage of games at home (57.1%) than road games (45.5%).
  • As a moneyline favorite, Creighton has won a higher percentage of its games at home (.900) compared to away games (.000).

Recent trends

  • In their last 10 games, the Bluejays have been scoring 72.2 points per contest, an average that’s slightly lower than the 75.7 they’ve scored over the course of the 2025-26 season.
  • Creighton has been a little suspect on the defensive end of the floor recently, giving up 81.8 points per game over its last 10 outings compared to the 75.7 it has surrendered this year.
  • During their past 10 outings, the Bluejays are making 0.5 fewer three-pointers per game than their season long average (9.4 compared to 9.9 season-long), while shooting a higher percentage from deep in that span (34.9% compared to 34.8% season-long).

Creighton betting records this season

  • ATS Record: 9-19-0 (Home: 4-10-0; Away: 4-7-0)
  • ATS Record When Favored by 3.5+: 4-6-0 (As Favorite: 5-10-0; As Underdog: 4-9-0)
  • O-U-P: 13-15-0 (Home: 8-6-0; Away: 5-6-0)
  • Record When Moneyline Favorite: 10-4 (Home: 9-1; Away: 0-3)
  • Record When Moneyline Underdog: 3-10 (Home: 0-3; Away: 3-5)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
45.4 (171st in nation) 45.4 (253rd) 31.9 (196th) 33.1 (300th) 15.5 (87th) 10.5 (124th)

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DePaul statistics, trends and more

As the away team

  • Against the spread, DePaul has had better results on the road (6-3-0) than at home (9-7-0).
  • Blue Demons games have finished above the over/under 37.5% of the time at home (six of 16), and 22.2% of the time away (two of nine).
  • This year the Blue Demons are 2-3 at home as moneyline underdogs (.400 winning percentage). On the road they are 2-7 (.222).

Recent trends

  • Over their last 10 games, the Blue Demons are scoring 69.1 points per contest, compared to their season average of 71.5.
  • DePaul is giving up 71.7 points per game in its previous 10 games, compared to its season average of 69.8 points allowed.
  • The Blue Demons are making 7.5 three-pointers per contest over their previous 10 games, which is 0.2 more than their average for the season (7.3). That said, they sport a worse shooting percentage from downtown over their previous 10 contests (31.4%) compared to their season average (32.6%).

DePaul betting records this season

  • ATS Record: 16-11-0 (Home: 9-7-0; Away: 6-3-0)
  • ATS Record When Underdog by 3.5+: 7-6-0 (As Favorite: 7-5-0; As Underdog: 9-6-0)
  • O-U-P: 9-18-0 (Home: 6-10-0; Away: 2-7-0)
  • Record When Moneyline Favorite: 10-2 (Home: 9-2; Away: 0-0)
  • Record When Moneyline Underdog: 4-11 (Home: 2-3; Away: 2-7)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
44.0 (258th in nation) 43.5 (135th) 30.5 (268th) 30.4 (146th) 15.3 (98th) 11.1 (197th)
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