Tigers vs. Guardians Betting Lines, Odds, & Player Matchups September 16, 2025

Data Skrive
Data Skrive

Casey Mize’s Detroit Tigers (85-65) are favored (-144) against the Cleveland Guardians (78-71), who are at +121, on Tuesday as he looks to pick up his 15th win of the season. The contest begins at 6:40 p.m. ET. Detroit’s Mize and Cleveland’s Joey Cantillo will start this matchup.

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Moneyline

Tigers to win vs Guardians -144

Bet $20, Payout $33.89

Tigers vs. Guardians betting lines

  • Favorite: Tigers (-144)
  • Underdog: Guardians (+121)
  • Over/under: 8

Tigers betting info, hitting leaders, & pitching

Tigers betting info

  • The Tigers are 63-41 in games they were listed as the moneyline favorite (winning 60.6% of those games).
  • Detroit has gone 43-20 (winning 68.3% of its games) when playing as moneyline favorites of -144 or shorter.
  • Based on this contest’s moneyline, the Tigers’ implied win probability is 59%.
  • Detroit has played in 150 games with set over/under, and have combined with opponents to go over the total 79 times (79-64-7).
  • The Tigers have covered 48% of their games this season, going 72-78-0 against the spread.

Tigers hitting info

  • Gleyber Torres has 21 doubles, 15 home runs and 82 walks while batting .255.
  • Among batters in MLB action, Torres ranks 128th in home runs and 65th in RBI.
  • Riley Greene has hit 34 home runs with 108 runs batted in while hitting .265. Those stats are all team-highs.
  • Greene ranks ninth in home runs among hitters in MLB action and fifth in RBI.
  • Spencer Torkelson is batting .237 with 26 doubles, a triple, 28 home runs and 68 walks.
  • Torkelson has safely hit in two straight games. During his last five outings he is hitting .316 with three walks.
  • Zach McKinstry has 21 doubles, 11 triples, 11 home runs and 45 walks while batting .261.

Tigers pitching rankings

  • The 8.6 strikeouts per nine innings compiled by the Tigers pitching staff ranks 12th in MLB.
  • Detroit has the 12th-ranked team ERA among all MLB pitching staffs (3.91).
  • The Tigers have the eighth-lowest WHIP in baseball (1.239).
  • The Tigers surrender the 15th-fewest home runs in baseball (174 total, 1.2 per game).
  • In its 2-0 win last time out, Detroit struck out eight Marlins batters while allowing seven hits.

Guardians betting info, hitting leaders, & pitching

Guardians betting info

  • This season, the Guardians have been the underdog 82 times and won 37, or 45.1%, of those games.
  • Cleveland is 20-17 this season when entering a game as the underdog by +121 or more on the moneyline.
  • The implied probability of a win by the Guardians, based on the moneyline, is 45.2%.
  • Cleveland and its opponents have gone over the total this season in 62 of its 147 opportunities.
  • The Guardians are 76-71-0 against the spread in their 147 chances this season.

Guardians hitting info

  • Jose Ramirez is batting .281 with 28 home runs and 77 RBI. All three of those stats are tops among Cleveland hitters this season.
  • Among all batters in the big leagues, Ramirez’s home run total is 24th, and his RBI total is 47th.
  • Steven Kwan has collected 156 hits this season and has an OBP of .333. He’s slugging .375 on the year.
  • Kwan ranks 196th in homers and 174th in RBI among all major league hitters this year.
  • Kyle Manzardo has collected 100 base hits, an OBP of .320 and a slugging percentage of .466 this season.
  • Angel Martinez is batting .227 with an OBP of .267 and a slugging percentage of .365 this season.

Guardians pitching rankings

  • The Guardians average the 16th-most strikeouts per nine innings (8.4) in the majors this season.
  • Cleveland has pitched to a 3.81 ERA this season, which ranks sixth in baseball.
  • The Guardians rank 16th in MLB with a combined 1.289 WHIP this season.
  • The Guardians have allowed the eighth-fewest home runs this season at just 157, or 1.1 per game.
  • Last time out, Cleveland defeated the White Sox, 3-2, with 11 strikeouts and five hits allowed.
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