The No. 4 Duke Blue Devils (18-1, 7-0 ACC) are 8.5-point favorites as they attempt to extend a seven-game win streak when they host the No. 20 Louisville Cardinals (14-5, 4-3 ACC) on Monday, January 26, 2026 at Cameron Indoor Stadium. The contest airs at 7 p.m. ET on ESPN. The over/under for the matchup is 157.5.
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Duke Cover -8.5 vs Louisville -110
Duke vs. Louisville betting lines
- Duke moneyline odds to win: -455
- Louisville moneyline odds to win: +346
- Spread: Duke (-8.5)
- Total: 157.5
Duke statistics, trends and more
As the home team
- Duke owns a worse record against the spread when playing at home (3-6-0) than it does on the road (5-1-0).
- In home games, the Blue Devils exceed the total 33.3% of the time (three of nine games). They hit the over in the same percentage of away games (two of six contests).
- In seven home games as a moneyline favorite, Duke has seven wins (1.000). It sports an identical winning percentage (5-0 record) as a moneyline favorite in road games.
Recent trends
- The Blue Devils’ offense has been less productive over their last 10 games, scoring 82.7 points a contest compared to the 85.7 they’ve averaged this year.
- The past 10 games have seen Duke allow 5.1 more points per game (70.4) than its season-long average (65.3).
- The Blue Devils are trending down from beyond the arc during their last 10 outings, making 8.4 threes per game and shooting 32.8% from long range in comparison to their season-long averages of 9.2 makes and 34.4% from distance in the 2025-26 season.
Duke betting records this season
- ATS Record: 10-9-0 (Home: 3-6-0; Away: 5-1-0)
- ATS Record When Favored by 8.5+: 8-9-0 (As Favorite: 10-9-0; As Underdog: 0-0-0)
- O-U-P: 6-13-0 (Home: 3-6-0; Away: 2-4-0)
- Record When Moneyline Favorite: 15-1 (Home: 7-0; Away: 5-0)
- Record When Moneyline Underdog: 0-0 (Home: 0-0; Away: 0-0)
| Field Goal % | Opp. Field Goal % | Rebounds | Opp. Rebounds | Assists | Turnovers |
|---|---|---|---|---|---|
| 49.8 (22nd in nation) | 39.3 (18th) | 37.4 (19th) | 27.6 (24th) | 17.3 (39th) | 11.2 (169th) |
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Louisville statistics, trends and more
As the away team
- Louisville has been better against the spread at home (7-5-0) than away (2-3-0) this season.
- In 2025-26 a lower percentage of the Cardinals’ games have finished above the over/under at home (33.3%, four of 12) than on the road (40%, two of five).
- The Cardinals’ winning percentage at home when moneyline underdogs is .000, both at home (0-1) and on the road (0-1).
Recent trends
- The Cardinals are posting 82.4 points per contest in their past 10 games, which is 5.4 fewer points than their average for the season (87.8).
- Louisville is giving up 71.5 points per game in its past 10 games, compared to its season average of 69.6 points allowed.
- The Cardinals are making 0.6 fewer threes per contest in their previous 10 games (11.3) compared to their season average (11.9), and they are putting up a worse three-point percentage over their past 10 contests (34.7%) compared to their season mark (35.3%).
Louisville betting records this season
- ATS Record: 11-8-0 (Home: 7-5-0; Away: 2-3-0)
- O-U-P: 7-12-0 (Home: 4-8-0; Away: 2-3-0)
- Record When Moneyline Favorite: 13-3 (Home: 9-1; Away: 2-2)
- Record When Moneyline Underdog: 0-2 (Home: 0-1; Away: 0-1)
| Field Goal % | Opp. Field Goal % | Rebounds | Opp. Rebounds | Assists | Turnovers |
|---|---|---|---|---|---|
| 46.9 (97th in nation) | 39.3 (18th) | 39 (seventh) | 30.3 (136th) | 17.8 (22nd) | 11.3 (175th) |

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