The Duke Blue Devils (1-2) face a fellow ACC opponent when they host the NC State Wolfpack (3-0) on Saturday, September 20, 2025 at Brooks Field at Wallace Wade Stadium.

The Blue Devils are the favorites (-3) in their matchup against the Wolfpack, with the over/under at 56.5 points. (In terms of the moneyline, the Blue Devils are -150 and the Wolfpack are +125.)

Keep reading for our betting preview for this this contest between the Blue Devils and the Wolfpack, and discover all of our predictions here, too!

Duke vs. NC State betting lines

• Spread favorite: Blue Devils (-3)
• Moneyline: Blue Devils (-150), Wolfpack (+125)
• Total: 56.5 points
• TV Channel: ESPN2
• Live Stream: Fubo

Duke vs. NC State betting info and stats

Duke has not won a game against the spread so far this season (0-3-0). Duke has yet to cover the spread when playing as favorites by at least 3 points (a 0-1 ATS record). In one game as a moneyline favorite, Duke won. NC State has won two games against the spread so far this season (2-1-0). NC State has not been an underdog on the moneyline yet this season.

Duke vs. NC State key players

Duke Blue Devils

• Darian Mensah has racked up 1,036 yards (345.3 ypg) on 80-of-119 passing with eight touchdowns compared to two interceptions this season.
• Nate Sheppard has racked up 127 yards on 15 carries.
• Jaquez Moore has been handed the ball 24 times this year and racked up 115 yards (38.3 per game) with one touchdown. He’s also contributed in the passing game with four grabs for 44 yards
• Cooper Barkate has hauled in 14 receptions for 272 yards (90.7 yards per game) to lead the team so far this season. .
• Sean Brown has hauled in 13 receptions totaling 191 yards so far this campaign.
• Andrel Anthony has a total of 121 receiving yards so far this year, grabbing 10 passes and scoring three touchdowns.
• Vincent Anthony Jr. paces the team with five sacks, and also has five TFL and 12 tackles.
• Duke’s leading tackler, Caleb Weaver, has 20 tackles this year.

NC State Wolfpack

• CJ Bailey has thrown for 719 yards (239.7 ypg) to lead NC State, completing 70.8% of his passes and tossing five touchdown passes and one interception this season. He is also a playmaker on the ground, racking up 84 yards (28 ypg) on 21 carries with three touchdowns.
• Daylan Smothers has rushed for 380 yards on 63 carries so far this year while scoring three times on the ground.
• Wesley Grimes has racked up 173 receiving yards on nine receptions to pace his squad so far this season while scoring one touchdown as a receiver.
• Noah Rogers has eight receptions (on 14 targets) for a total of 109 yards (36.3 yards per game) and one touchdown this year.
• Terrell Anderson’s nine catches (on 13 targets) have netted him 107 yards (35.7 ypg).
• Caden Fordham has racked up one sack to pace the team, while also recording two TFL and 25 tackles.
• Brown, NC State’s top tackler, has 29 tackles and three TFL this year.
• Cian Slone has picked off a team-high one pass. He also has 13 tackles, one TFL, and one pass defended to his name.