The No. 25 Florida State Seminoles (3-2) meet a conference opponent when they host the Pittsburgh Panthers (3-2) on Saturday, October 11, 2025 at Bobby Bowden Field at Doak Campbell Stadium in an ACC clash.

The Seminoles are expected to win by at least two scores (currently -10.5) versus the Panthers. The over/under for this game is 57.5 points.

Read on for our preview for this this game between the Seminoles and the Panthers, and discover all of our expert predictions here, too!

Florida State vs. Pittsburgh betting lines

• Spread favorite: Seminoles (-10.5)
• Moneyline: Seminoles (-415), Panthers (+322)
• Total: 57.5 points
• TV Channel: ESPN
• Live Stream: Fubo

Florida State vs. Pittsburgh betting info and stats

Florida State has a pair of wins against the spread so far this season (2-2-0). Florida State is undefeated ATS (1-0) when favorites by at least 10.5 points. Florida State has split them games as the moneyline favorite this season. Pittsburgh has a 3-2-0 record against the spread so far this season. Pittsburgh has played as an underdog on the moneyline once so far this season, and failed to pick up the victory.

Florida State vs. Pittsburgh recent stats and trends

Florida State Seminoles

Pittsburgh Panthers

• Pittsburgh is 1-2 against the spread and 1-2 overall during its past three games.
• The final combined score of the last three Pittsburgh games surpassed the set total one time.
• Pittsburgh’s last three outings have ended with an average of 55.3 points scored. That’s 2.2 fewer points than this contest’s over/under.

Florida State vs. Pittsburgh key players

Florida State Seminoles

• Thomas Castellanos has thrown for 1,120 yards, completing 60.9% of his passes and recording six touchdowns and five interceptions this season. He’s also run for 274 yards (54.8 ypg) on 57 carries with four rushing touchdowns.
• Gavin Sawchuk has racked up 281 yards on 53 carries while finding paydirt six times as a runner. He’s also caught six passes for 85 yards (21.3 per game) and one touchdown through the air.
• Duce Robinson’s team-high 433 yards as a receiver have come on 23 catches (out of 37 targets) with three touchdowns.
• Micahi Danzy has put together a 197-yard season so far, hauling in nine passes on 13 targets.
• Lawayne McCoy has a total of 113 receiving yards so far this year, hauling in seven throws and scoring one touchdown.
• Ashlynd Barker has 2.0 sacks to lead the team, and also has 2.0 TFL and 14 tackles.
• Florida State’s leading tackler, Earl Little II, has 35 tackles and one interception this year.
• Jeremiah Wilson has picked off a team-leading two passes. He also has 12 tackles and two passes defended to his name.

Pittsburgh Panthers

• Eli Holstein has recored 1,058 passing yards, or 211.6 per game, so far this season. He has completed 62.7% of his passes and has collected 11 touchdowns with five interceptions. He’s also helped out on the ground with 16.6 rushing yards per game while scoring as a runner one time.
• Juelz Goff has run for 175 yards on 45 carries so far this year while scoring three times on the ground. He’s also added seven catches, totaling 63 yards.
• Desmond Reid has racked up 142 yards (on 24 attempts) with one touchdown, while also catching six passes for 71 yards.
• Raphael Williams leads his team with 360 receiving yards on 19 receptions with four touchdowns.
• Kenny Johnson has caught 20 passes and compiled 252 receiving yards (50.4 per game) with two touchdowns.
• Cataurus Hicks has racked up 197 reciving yards (39.4 ypg) and three touchdowns this season.
• Blaine Spires has racked up 2.5 sacks to pace the team, while also picking up 4.0 TFL and 12 tackles.
• Rasheem Biles is the team’s top-tackler this year. He’s picked up 43 tackles, 5.0 TFL, two sacks, and one interception.
• Braylan Lovelace has a team-high one interception to go along with 30 tackles, 3.0 TFL, and one pass defended.