The Houston Astros (36-30) host the Chicago White Sox (23-44) on Wednesday at 8:10 p.m. ET. The Astros are moneyline favorites (-181) against the underdog White Sox (+150). Houston’s Ryan Gusto and Chicago’s Sean Burke pitch first for their squads in this matchup.

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Astros vs. White Sox betting lines

• Favorite: Astros (-181)
• Underdog: White Sox (+150)
• Over/under: 8.5

Astros betting info, hitting leaders, & pitching

Astros betting info

• The Astros are 25-20 in games they were listed as the moneyline favorite (winning 55.6% of those games).
• When it has played as moneyline favorites with odds of -181 or shorter, Houston has a 3-1 record (winning 75% of its games).
• Based on this game’s moneyline, the Astros’ implied win probability is 64.4%.
• Houston has had an over/under set by oddsmakers 66 times, and have combined with opponents to go over the total in 26 of those games (26-38-2).
• The Astros have collected a 35-31-0 record against the spread this season (covering 53% of the time).

Astros hitting info

• Jeremy Pena paces the Astros with a team-high batting average of .319.
• In MLB play, Pena ranks 67th in homers and 69th in RBI.
• Isaac Paredes’ 14 home runs and 39 runs batted in both lead his team.
• Paredes ranks 14th in home runs and 28th in RBI among hitters in baseball.
• Jose Altuve is hitting .266 with six doubles, nine home runs and 18 walks.
• Jake Meyers is hitting .300 with 11 doubles, a triple, three home runs and 19 walks.
• Meyers has safely hit in four games in a row. During his last five outings he is batting .389 with a double and three walks.

Astros pitching rankings

• The Astros pitching staff is No. 1 in MLB with a collective 9.9 strikeouts per nine innings.
• Houston’s 3.54 team ERA ranks seventh among all MLB pitching staffs.
• Astros pitchers combine for the No. 3 WHIP in the majors (1.168).
• The Astros allow the sixth-fewest home runs in baseball (63 total, one per game).
• Houston struck out 13 White Sox batters while giving up four hits in a 4-2 loss in its last game.

White Sox betting info, hitting leaders, & pitching

White Sox betting info

• The White Sox have won 23, or 34.3%, of the 67 games they’ve played as underdogs this season.
• This season, Chicago has won 11 of its 40 games, or 27.5%, when it’s the underdog by at least +150 on the moneyline.
• The implied probability of a win by the White Sox, based on the moneyline, is 40%.
• Chicago’s games have gone over the total in 30 of its 67 chances.
• The White Sox are 39-28-0 against the spread in their 67 chances this season.

White Sox hitting info

• Miguel Vargas is batting .233 this season with a team-high nine home runs and 29 RBI.
• Among all hitters in MLB, Vargas’ home run total is 67th, and his RBI total is 91st.
• Chase Meidroth has 46 hits and an OBP of .383 to go with a slugging percentage of .363 this season.
• Among all MLB batters, Meidroth ranks 264th in home runs and 300th in RBI.
• Andrew Benintendi is slashing .241/.315/.421 this season for the White Sox.
• Luis Robert has collected 38 hits this season and has an OBP of .269. He’s slugging .304 on the year.

White Sox pitching rankings

• The White Sox average just 9.9 strikeouts per nine innings as a pitching staff, which ranks 27th in the big leagues.
• Chicago pitchers have a combined ERA of 4.10 ERA this year, which ranks 19th in MLB.
• White Sox pitchers have a 1.377 WHIP this season, 25th in the majors.
• The White Sox have allowed the 17th-fewest home runs this season with 72, or 1.1 per game.
• Chicago earned a 4-2 win in its most recent game, striking out six Astros batters while allowing nine hits.