Houston vs. Arizona betting: College basketball preview for Feb. 21

Data Skrive
Data Skrive

The No. 2 Houston Cougars (23-3, 11-2 Big 12) are favored (by 6.5 points) to build on an 11-game home win streak when they host the No. 4 Arizona Wildcats (24-2, 11-2 Big 12) on Saturday, February 21, 2026 at 3 p.m. ET. The matchup has an over/under set at 141.5 points.

Check out all the Latest NCAA Basketball Betting Previews!

Spread

Houston Cover -6.5 vs Arizona -108

Bet $20, Payout $38.52

Houston vs. Arizona betting lines

  • Houston moneyline odds to win: -287
  • Arizona moneyline odds to win: +227
  • Spread: Houston (-6.5)
  • Total: 141.5

Houston statistics, trends and more

As the home team

  • Against the spread, Houston has performed better when playing at home, covering eight times in 13 home games, and four times in seven road games.
  • The Cougars have exceeded the over/under less often when playing at home, hitting the over in three of 13 home matchups (23.1%). In road games, they have hit the over in three of seven games (42.9%).
  • Houston has performed better as a moneyline favorite at home, putting up a home record of 10-0, compared to going 4-1 in road games.

Recent trends

  • The Cougars have seen an increase in scoring lately, racking up 78.8 points per game in their last 10 contests, 1.0 point more than the 77.8 they’ve scored this season.
  • Houston’s defense has been less stingy lately, as the team has given up 64.2 points per game during its past 10 compared to the 61.6 points per game its opponents are averaging this season.
  • The Cougars are trending up from beyond the arc during their last 10 outings, making 9.0 threes per game and shooting 35.0% from long range in comparison to their season-long averages of 8.9 makes and 34.1% from distance in the 2025-26 season.

Houston betting records this season

  • ATS Record: 14-12-0 (Home: 8-5-0; Away: 4-3-0)
  • ATS Record When Favored by 6.5+: 11-9-0 (As Favorite: 14-11-0; As Underdog: 0-1-0)
  • O-U-P: 11-15-0 (Home: 3-10-0; Away: 3-4-0)
  • Record When Moneyline Favorite: 19-2 (Home: 10-0; Away: 4-1)
  • Record When Moneyline Underdog: 0-1 (Home: 0-0; Away: 0-1)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
45.2 (178th in nation) 39.7 (18th) 33.0 (127th) 28.7 (50th) 15.3 (94th) 7.8 (first)

Need to know more about sports betting before you put down a wager on Houston vs. Arizona? Here’s everything you need to know about how to bet.

Arizona statistics, trends and more

As the away team

  • Against the spread, Arizona has had better results away (4-3-0) than at home (7-8-0).
  • In terms of the over/under, Wildcats games have gone over less frequently at home (eight of 15, 53.3%) than on the road (four of seven, 57.1%).

Recent trends

  • The Wildcats have fared worse offensively in their past 10 games, scoring 82.3 points per contest, 5.4 fewer points their than season average of 87.7.
  • Arizona is giving up 69.5 points per contest over its previous 10 games, compared to its season average of 68.6 points allowed.
  • The Wildcats are sinking 4.9 treys per game over their last 10 games, which is 1.0 fewer three-pointers than their average for the season (5.9). In addition, they have a lower three-point percentage over their previous 10 contests (32.9%) compared to their season average from downtown (35.6%).

Arizona betting records this season

  • ATS Record: 15-11-0 (Home: 7-8-0; Away: 4-3-0)
  • O-U-P: 13-13-0 (Home: 8-7-0; Away: 4-3-0)
  • Record When Moneyline Favorite: 20-2 (Home: 12-1; Away: 5-1)
  • Record When Moneyline Underdog: 2-0 (Home: 0-0; Away: 1-0)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
50.5 (12th in nation) 39.1 (eighth) 40.7 (second) 27.4 (19th) 17.7 (23rd) 11.0 (181st)
Author Profile
BetDecider Team

The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.

Ryan Knuppel

Knup Solutions [molongui_author_name]

About Ryan Knuppel

Ryan has been one of the leading sports business & iGaming professionals for over 15 years. He started as a freelance writer and now operates one of the top sports content agencies around, Knup Solutions. He has literally written 10,000 plus sports and betting related articles across the web.

 

Sports Network:

sports20.com, usawager.com, knupsports.com, baseballspotlight.com, basketballarticles.com, betdecider.com, njsportsbookreview.com, dunkelindex.com, sportspub.com, oddschoice.com

 

Betting Guide

How Money Line Works?

Moneyline betting is by far the easiest way to place a sports wager. There are no point spreads to parse, no garbage-time free throws to ruin your betting day, and no last-minute meaningless touchdowns to take you from a winner to a loser.

How to Bet Odds

When we, as sports fans, learned our multiplication tables, we aced the number 7. Seven, 14, 21, 28, 35, 42 were easy because we all watched football on the weekends. Multiplication by sevens, then add a three, a six after a missed PAT.

How to Bet on NFL Games

Baseball is America’s pastime, but football is America’s crazed passion, with its weekly schedule of games, millions of television viewers across the country and the world, and the billion-dollar stadiums that serve as Sunday cathedrals in 32 American cities.

What is the Spread?

If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …