Indiana vs. Siena betting: College basketball preview for Dec. 22

Data Skrive
Data Skrive

The Indiana Hoosiers (9-3) hit the court against the Siena Saints (9-3) as heavy, 22.5-point favorites on Monday, December 22, 2025 at 6 p.m. ET on Big Ten Network. The over/under is 143.5 in the matchup.

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Indiana Cover -22.5 vs Siena -108

Bet $20, Payout $38.52

Indiana vs. Siena betting lines

  • Indiana moneyline odds to win: -6667
  • Siena moneyline odds to win: +1800
  • Spread: Indiana (-22.5)
  • Total: 143.5

Indiana statistics, trends and more

As the home team

  • Indiana owned a better record against the spread in home games (11-7-0) than it did on the road (5-5-0) last season.
  • The Hoosiers exceeded the total more often at home last year, hitting the over in eight of 18 home matchups (44.4%). In road games, they hit the over in three of 10 games (30%).
  • Indiana, as a moneyline favorite, had an identical winning percentage when playing at home (13-0 record) and on the road (1-0 record) last season.

Last season stats

  • At 74.7 points scored per game and 72.0 points allowed last year, the Hoosiers were 147th in the country offensively and 182nd defensively.
  • With 32.7 rebounds per game and 30.3 rebounds allowed, Indiana was 142nd and 121st in college basketball, respectively, last season.
  • The Hoosiers were 42nd in college basketball in assists (15.9 per game) last year.

Indiana betting records this season

  • ATS Record: 6-6-0 (Home: 5-3-0; Away: 0-2-0)
  • ATS Record When Favored by 22.5+: 3-3-0 (As Favorite: 6-4-0; As Underdog: 0-2-0)
  • O-U-P: 6-6-0 (Home: 4-4-0; Away: 0-2-0)
  • Record When Moneyline Favorite: 9-1 (Home: 8-0; Away: 0-1)
  • Record When Moneyline Underdog: 0-2 (Home: 0-0; Away: 0-1)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
48.6 (61st in nation) 38.9 (26th) 32.9 (199th) 28.5 (66th) 19.7 (12th) 10.3 (77th)

Need to know more about sports betting before you put down a wager on Indiana vs. Siena? Here’s everything you need to know about how to bet.

Siena statistics, trends and more

As the away team

  • Against the spread, Siena has an identical winning percentage (.600) at home (3-2-0 record) and on the road (3-2-0).
  • In terms of the over/under, Saints games have gone over less frequently at home (one of five, 20%) than away (three of five, 60%).

Last season stats

  • With 72.2 points per game on offense, the Saints were 225th in the country last year. On defense, they gave up 72.1 points per contest, which ranked 185th in college basketball.
  • Siena averaged 29.7 rebounds per game (310th-ranked in college basketball). It allowed 31.1 rebounds per contest (172nd-ranked).
  • The Saints ranked 300th in the nation with 11.8 assists per contest.

Siena betting records this season

  • ATS Record: 7-5-0 (Home: 3-2-0; Away: 3-2-0)
  • O-U-P: 4-8-0 (Home: 1-4-0; Away: 3-2-0)
  • Record When Moneyline Favorite: 9-1 (Home: 4-1; Away: 3-0)
  • Record When Moneyline Underdog: 0-2 (Home: 0-0; Away: 0-2)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
45.9 (158th in nation) 44.2 (219th) 31.2 (269th) 27.6 (45th) 13.2 (267th) 10.3 (77th)
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