James Conner Player Prop Bets and Odds: Cardinals vs. 49ers | September 21, 2025

Data Skrive
Data Skrive

Levi’s Stadium features Week 3 action as the Arizona Cardinals and James Conner take on the San Francisco 49ers at 4:25 p.m. ET on Sunday. With prop bets available for Conner in this outing, let’s dig into the stats and trends that will help determine the best bets for this game.

Rushing Yards Prop

James Conner to go over 52.5 yards

Bet $20, Payout $37.39

James Conner Prop Lines

  • Matchup: Arizona Cardinals at San Francisco 49ers
  • Time: 4:25 p.m. ET
  • Date: September 21, 2025
  • Rushing yards prop: Over 52.5 (-115)
  • Receiving yards prop: Over 15.5 (-110)

James Conner Stats and Trends

  • Conner has totaled 73 yards on 23 carries (36.5 ypg). He has scored one TD on the ground.
  • Conner’s rushing yards over/under is 52.5, compared to his season average of 36.5.
  • Conner hasn’t run for over 52.5 yards in a game this season (in two opportunities).
  • He rushes for 35.5 fewer yards per game than his average over/under (72).
  • Conner has failed to reach his rushing yards over/under in each of his two games.
  • He has had one game with a rushing touchdown.
  • Conner has also caught five balls for 23 yards (11.5 ypg). Conner’s scored one TD through the passing game.

Recent Performances vs. the 49ers

Week Opponent Rush Yards Allowed Rush TDs Allowed
1 Seahawks 84 1
2 Saints 121 0

Cardinals Away Splits (Last Season)

  • On the road last year, the Cardinals averaged fewer points (20 per game) than overall (23.5). They also conceded more (25.8 per game) than overall (22.3).
  • On the road, the Cardinals picked up fewer yards (350.3 per game) than overall (358.2). They also gave up more (344.6 per game) than overall (342.5).
  • On the road last season, the Cardinals picked up more passing yards (227 per game) than they did overall (214.1). They also gave up fewer passing yards in road games (212.6) than they did overall (216.1).
  • The Cardinals accumulated 123.3 rushing yards per game in away games (20.9 fewer than overall), and allowed 132 on the road (5.6 more than overall).
  • The Cardinals converted fewer third downs on the road in 2024 (42.3%) than they did overall (43.0%) and allowed opponents to convert on more third downs in road games (48%) than overall (43.8%).
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About Ryan Knuppel

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