Week 11 NFL action pits James Cook and his Buffalo Bills teammates up against the Tampa Bay Buccaneers at 1 p.m. ET on Sunday Let’s take a look at Cook’s prop bets available for this matchup, and break down his stats and trends to figure out the top value picks.

James Cook Prop Lines

• Matchup: Buffalo Bills vs. Tampa Bay Buccaneers
• Time: 1 p.m. ET
• Date: November 16, 2025
• Rushing yards prop: Over 80.5 (-113)
• Receiving yards prop: Over 10.5 (-117)

James Cook Stats and Trends

• Cook leads the team with 920 yards (102.2 ypg) on 166 carries and has scored seven rushing scores.
• Cook’s rushing yards over/under is 80.5, compared to his season average of 102.2.
• In 66.7% of his games (six of nine), Cook has rushed for more than 80.5 yards.
• His rushing yards average of 102.2 is 30.6 higher than his over/under average (71.6).
• Cook has gone over his rushing yards prop bet six times (in nine opportunities) this year.
• He has scored a rushing TD in five games, with multiple rushing touchdowns two times.
• Cook has recorded 18 catches for 124 yards (13.8 yypg).

Recent Performances vs. the Buccaneers

Bills Home Splits

• At home, the Bills score 30.2 points per game and give up 24.8. That’s more than they score (27.6) and allow (21.9) overall.
• The Bills rack up 396 yards per game at home (11.6 more than their overall average), and give up 329.8 at home (12 more than overall).
• In home games, the Bills rack up 258.2 passing yards per game and give up 188.4. That’s more than they gain (231.2) and allow (170.2) overall.
• The Bills accumulate 137.8 rushing yards per game at home (15.4 less than their overall average), and give up 141.4 at home (6.2 less than overall).
• At home, the Bills convert 49.1% of third downs and allow 44.3% to be converted. That’s more than they convert (43.9%) and allow (37.5%) overall.