Kyler Murray’s Arizona Cardinals face the NFC’s San Francisco 49ers at 4:25 p.m. ET on Sunday in Week 3 of the 2025 NFL campaign. In this piece, we’ll dig into Murray’s stats and trends to help you pick out the best bets among his props for this outing.
Passing Yards Prop
Bet $20, Payout $38.02
Kyler Murray to go over 217.5 yards
Kyler Murray Prop Lines
- Matchup: Arizona Cardinals at San Francisco 49ers
- Time: 4:25 p.m. ET
- Date: September 21, 2025
- Passing yards prop: Over 217.5 (-111)
- Rushing yards prop: Over 28.5 (-108)
Kyler Murray Stats and Trends
- Kyler Murray has thrown for 383 yards (191.5 per game), completing 70.4% of his throws, with three TDs and one INT.
- Murray passes for 191.5 yards per game. That’s 26.0 fewer yards than his over/under on Sunday.
- In two contests this season, Murray has exceeded 217.5 passing yards on one occasion.
- His average passing yards prop this season is 221.5 passing yards, while his actual passing average is under that by 30.0 yards.
- This year, Murray has not surpassed his passing yards prop total in two games.
- He has thrown for a touchdown in all two games this season, including more than one touchdown pass one time.
- Murray has also helped out via the running game, with 70 yards (35.0 per game) on 14 attempts.
Recent Performances vs. the 49ers
| Week | Opponent | Pass Yards Allowed | Pass TDs Allowed |
|---|---|---|---|
| 1 | Seahawks | 146 | 0 |
| 2 | Saints | 186 | 3 |
Cardinals Away Splits (Last Season)
- On the road last year, the Cardinals scored fewer points (20 per game) than overall (23.5). They also allowed more (25.8 per game) than overall (22.3).
- The Cardinals picked up 350.3 yards per game in road games (7.9 fewer than overall), and gave up 344.6 in road games (2.1 more than overall).
- The Cardinals accumulated 227 passing yards per game in away games last season (12.9 more than overall), and gave up 212.6 in road games (3.5 fewer than overall).
- On the road, the Cardinals accumulated fewer rushing yards (123.3 per game) than overall (144.2). They also allowed more rushing yards (132 per game) than overall (126.4).
- The Cardinals successfully converted 42.3% of third downs away from home in 2024 (0.7% less than overall), and conceded on 48% of third downs in road games (4.2% more than overall).
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