Kyren Williams and his Los Angeles Rams teamates will hit the field against the San Francisco 49ers at 4:25 p.m. ET on Sunday in Week 10 of the 2025 NFL season. In this article we dig into all of Williams’ prop bets available for this matchup, and examine the stats to figure out the best predictions.

Kyren Williams Prop Lines

• Matchup: Los Angeles Rams at San Francisco 49ers
• Time: 4:25 p.m. ET
• Date: November 9, 2025
• Rushing yards prop: Over 64.5 (-110)
• Receiving yards prop: Over 16.5 (-113)

Kyren Williams Stats and Trends

• Williams has put up a team-best 586 yards on 132 carries (73.3 ypg). He has scored three TDs on the ground.
• Williams’ rushing yards over/under is 64.5, compared to his season average of 73.3.
• Williams has had more than 64.5 rushing yards in six games this season (75.0%).
• The average rushing yards prop he has had this season (70.1) is just a bit lower than his average total (73.3).
• Williams has gone over his rushing yards prop bet three times (in eight opportunities) this year.
• He has rushed for a TD in three games.
• Williams also has hauled in 20 passes for 166 yards and three touchdowns.

Recent Performances vs. the 49ers

Rams Away Splits

• The Rams score 27.8 points per game in away games (1.7 more than overall) and allow 15.5 in road games (0.4 fewer than overall).
• The Rams pick up 326.8 yards per game in road games (43.1 fewer than overall), and concede 298.5 away from home (4.4 fewer than overall).
• The Rams accumulate 208.8 passing yards per game in road games (49.2 fewer than overall), and concede 181.5 away from home (21.6 fewer than overall).
• The Rams accumulate more rushing yards in road games (118 per game) than they do overall (111.9), but they also concede more (117 per game) than overall (99.8).
• The Rams convert 33.3% of third downs in away games (6.3% less than overall), and allow opponents to convert on 34.4% of third downs in away games (1.4% more than overall).