Louisville vs. Indiana betting: College basketball preview for Dec. 6

Data Skrive
Data Skrive

The No. 22 Indiana Hoosiers (7-1) are underdogs (by 3.5 points) to continue a six-game home winning streak when they host the No. 6 Louisville Cardinals (7-1) on Saturday, December 6, 2025 at 2:15 p.m. ET. The point total is set at 160.5 in the matchup.

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Spread

Louisville Cover -3.5 vs Indiana -116

Bet $20, Payout $37.24

Louisville vs. Indiana betting lines

  • Louisville moneyline odds to win: -192
  • Indiana moneyline odds to win: +159
  • Spread: Louisville (-3.5)
  • Total: 160.5

Louisville statistics, trends and more

Last season stats

  • The Cardinals scored 78.5 points per game and allowed 69.5 last season, making them 65th in the country on offense and 89th on defense.
  • Louisville collected 34.6 rebounds per game and gave up 30.2 boards last season, ranking 47th and 114th, respectively, in the nation.
  • At 13.9 assists per game last season, the Cardinals were 148th in the nation.

Louisville betting records this season

  • ATS Record: 5-3-0 (Home: 4-2-0; Away: 0-1-0)
  • ATS Record When Favored by 3.5+: 5-2-0 (As Favorite: 5-3-0; As Underdog: 0-0-0)
  • O-U-P: 4-4-0 (Home: 3-3-0; Away: 1-0-0)
  • Record When Moneyline Favorite: 6-1 (Home: 5-0; Away: 0-1)
  • Record When Moneyline Underdog: 0-0 (Home: 0-0; Away: 0-0)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
47.2 (107th in nation) 36.9 (eighth) 42.4 (third) 31.6 (206th) 19.8 (10th) 10.3 (72nd)

Need to know more about sports betting before you put down a wager on Louisville vs. Indiana? Here’s everything you need to know about how to bet.

Indiana statistics, trends and more

Last season stats

  • The Hoosiers ranked 147th in college basketball last season with 74.7 points per game. At the other end, they ranked 182nd with 72.0 points allowed per game.
  • Indiana pulled down 32.7 rebounds per game (142nd-ranked in college basketball) last season, while allowing 30.3 rebounds per contest (121st-ranked).
  • The Hoosiers averaged 15.9 dimes per game, which ranked them 42nd in the nation.

Indiana betting records this season

  • ATS Record: 5-3-0 (Home: 4-2-0; Away: 0-1-0)
  • O-U-P: 4-4-0 (Home: 3-3-0; Away: 0-1-0)
  • Record When Moneyline Favorite: 7-1 (Home: 6-0; Away: 0-1)
  • Record When Moneyline Underdog: 0-0 (Home: 0-0; Away: 0-0)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
49.2 (53rd in nation) 37.6 (18th) 33.5 (188th) 28.8 (78th) 20.0 (seventh) 8.9 (16th)
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Betting Guide

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