The No. 6 seed Louisville Cardinals (22-9, 11-7 ACC) take on the No. 11 seed SMU Mustangs (20-12, 8-10 ACC) as 6.5-point favorites in the ACC Tournament Wednesday at Spectrum Center, starting at 2:30 p.m. ET on ESPN. Both teams will look to take one step closer to earning an automatic place in the NCAA Tournament bracket. The matchup has an over/under of 163.5 points.
Check out all the Latest NCAA Basketball Betting Previews!
Louisville Cover -6.5 vs SMU -117
Louisville vs. SMU betting lines
- Louisville moneyline odds to win: -315
- SMU moneyline odds to win: +244
- Spread: Louisville (-6.5)
- Total: 163.5
Louisville statistics, trends and more
Recent trends
- The Cardinals have been racking up 85.4 points per game in their last 10 appearances, an average that’s slightly lower than the 85.9 they’ve scored over the course of the 2025-26 campaign.
- Louisville has been less stingy on the defensive side of the ball as of late, allowing 76.6 points per game during its past 10 contests compared to the 72.5 points per game its opponents are averaging over the 2025-26 season.
- The Cardinals’ past 10 contests have seen them make 12.0 three-pointers per game while shooting 39.6% from beyond the arc. Both numbers are up from their 2025-26 averages of 11.9 makes and 36.3%.
Louisville betting records this season
- ATS Record: 16-15-0 (Home: 10-7-0; Away: 3-8-0)
- ATS Record When Favored by 6.5+: 13-7-0 (As Favorite: 15-12-0; As Underdog: 1-3-0)
- O-U-P: 13-18-0 (Home: 6-11-0; Away: 6-5-0)
- Record When Moneyline Favorite: 20-6 (Home: 14-1; Away: 3-5)
- Record When Moneyline Underdog: 1-3 (Home: 0-1; Away: 1-2)
| Field Goal % | Opp. Field Goal % | Rebounds | Opp. Rebounds | Assists | Turnovers |
|---|---|---|---|---|---|
| 47.2 (65th in nation) | 42.2 (62nd) | 36.5 (21st) | 30.2 (125th) | 17.4 (20th) | 11.4 (229th) |
Need to know more about sports betting before you put down a wager on Louisville vs. SMU? Here’s everything you need to know about how to bet.
SMU statistics, trends and more
Recent trends
- The Mustangs have fared worse offensively over their last 10 games, tallying 81.9 points per contest, 3.1 fewer points their than season average of 85.0.
- In its previous 10 games, SMU is giving up 78.7 points per contest, 0.6 more points than its season average (78.1).
- The Mustangs are sinking 9.2 treys per contest in their last 10 games, which is 0.8 more than their average for the season (8.4). Likewise, they own a better three-point percentage over their previous 10 contests (38.5%) compared to their season average from three-point land (37.6%).
SMU betting records this season
- ATS Record: 14-17-1 (Home: 8-10-0; Away: 4-6-1)
- ATS Record When Underdog by 6.5+: 1-2-0 (As Favorite: 8-12-0; As Underdog: 6-5-1)
- O-U-P: 19-13-0 (Home: 10-8-0; Away: 6-5-0)
- Record When Moneyline Favorite: 17-4 (Home: 14-1; Away: 2-3)
- Record When Moneyline Underdog: 3-8 (Home: 1-2; Away: 1-5)
| Field Goal % | Opp. Field Goal % | Rebounds | Opp. Rebounds | Assists | Turnovers |
|---|---|---|---|---|---|
| 49.2 (22nd in nation) | 43.5 (129th) | 34.3 (65th) | 30.6 (150th) | 17.2 (26th) | 10.8 (171st) |

BetDecider Team
The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.


