Louisville vs. Syracuse betting: College basketball preview for March 3

Data Skrive

The Syracuse Orange (15-14, 6-10 ACC) will attempt to stop a three-game losing streak when they visit the Louisville Cardinals (20-9, 9-7 ACC) on Tuesday, March 3, 2026 at KFC Yum! Center as big, 13.5-point underdogs. The matchup airs at 9 p.m. ET on ACC Network. The matchup’s over/under is set at 159.5.

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Spread

Louisville Cover -13.5 vs Syracuse -117

Bet $20, Payout $37.09

Louisville vs. Syracuse betting lines

  • Louisville moneyline odds to win: -1220
  • Syracuse moneyline odds to win: +732
  • Spread: Louisville (-13.5)
  • Total: 159.5

Louisville statistics, trends and more

As the home team

  • Louisville sports a better record against the spread when playing at home (9-7-0) than it does in road games (2-8-0).
  • When it comes to point totals, the Cardinals hit the over less often at home, as they’ve exceeded the total six times in 16 opportunities this season (37.5%). In road games, they have hit the over five times in 10 opportunities (50%).
  • As a moneyline favorite, Louisville has taken 13 of 14 games when playing at home, good for a .929 winning percentage. It has won three of eight games on the road (.375) as a moneyline favorite.

Recent trends

  • The Cardinals’ offense has been worse over their last 10 games, scoring 82.5 points a contest compared to the 86.0 they’ve averaged this season.
  • The past 10 games have seen Louisville give up 5.0 more points per game (77.2) than its season-long average (72.2).
  • While the Cardinals are hitting fewer threes per game over their past 10 contests (11.5 per game) in comparison to their season-long average (11.8), they are doing so while shooting a higher percentage (36.7% from beyond the arc over the last 10, 35.8% on the season).

Louisville betting records this season

  • ATS Record: 14-15-0 (Home: 9-7-0; Away: 2-8-0)
  • ATS Record When Favored by 13.5+: 6-5-0 (As Favorite: 14-12-0; As Underdog: 0-3-0)
  • O-U-P: 12-17-0 (Home: 6-10-0; Away: 5-5-0)
  • Record When Moneyline Favorite: 19-6 (Home: 13-1; Away: 3-5)
  • Record When Moneyline Underdog: 0-3 (Home: 0-1; Away: 0-2)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
47.0 (73rd in nation) 41.8 (53rd) 37.1 (16th) 30.3 (139th) 17.3 (23rd) 11.7 (252nd)

Need to know more about sports betting before you put down a wager on Louisville vs. Syracuse? Here’s everything you need to know about how to bet.

Syracuse statistics, trends and more

As the away team

  • Syracuse has been better against the spread away (4-4-0) than at home (8-9-0) this year.
  • In terms of the over/under, Orange games have gone over seven of 17 times at home (41.2%), and seven of eight away (87.5%).
  • As moneyline underdogs, the Orange have won a higher percentage of games at home (2-2) than away (1-5).

Recent trends

  • The Orange are averaging 76.3 points per game over their previous 10 games, which is 0.4 more than their average for the season (75.9).
  • Syracuse is giving up 84.8 points per game over its previous 10 games, which is 10.9 more points than it is allowing for the season (73.9).
  • The Orange are sinking 7.5 three-pointers per contest with a 33.6% three-point percentage over their previous 10 games, compared to their season averages of 7.2 and 33.7%.

Syracuse betting records this season

  • ATS Record: 14-15-0 (Home: 8-9-0; Away: 4-4-0)
  • ATS Record When Underdog by 13.5+: 2-1-0 (As Favorite: 8-8-0; As Underdog: 6-7-0)
  • O-U-P: 16-13-0 (Home: 7-10-0; Away: 7-1-0)
  • Record When Moneyline Favorite: 12-4 (Home: 10-3; Away: 1-1)
  • Record When Moneyline Underdog: 3-10 (Home: 2-2; Away: 1-5)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
47.1 (65th in nation) 44.1 (169th) 30.8 (250th) 33.2 (304th) 12.9 (255th) 10.7 (155th)
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