The Louisville Cardinals (3-2) hit the road for an ACC showdown against the Virginia Cavaliers (4-1) on Saturday, October 12, 2024 at Scott Stadium.

The Cardinals are solid favorites (-7) in their game versus the Cavaliers, with the over/under being 53.5 points. (In terms of the moneyline, the Cardinals are -273 and the Cavaliers are +219.)

Keep reading for our betting primer for this this game between the Cardinals and the Cavaliers, and discover all of our predictions here, too!

Louisville vs. Virginia betting lines

• Spread favorite: Cardinals (-7)
• Moneyline: Cardinals (-273), Cavaliers (+219)
• Total: 53.5 points
• TV Channel: ACCN
• Live Stream: Fubo (Watch for free)

Louisville vs. Virginia betting info and stats

Louisville has two wins against the spread so far this season (2-2-0). In two games played when favored by at least seven points, Louisville is undefeated ATS at 2-0. Louisville has been favored on the moneyline for three games this season, and it has recorded a 2-1 record in those matchups. Virginia, in five games with a set spread so far this season, has gone 3-1-1 against the spread. This will be the first time on the year Virginia is the moneyline underdog.

Louisville vs. Virginia recent stats and trends

Louisville Cardinals

Virginia Cavaliers

• Virginia is 2-1 against the spread in its past three games and has a 1-2 straight-up record in those contests.
• Virginia and its opponents have combined to hit the over in one of those games.
• The past three Virginia games averaged 0.2 fewer points (53.3) than this matchup’s point total.

Louisville vs. Virginia key players

Louisville Cardinals

• Tyler Shough has compiled 1,443 yards (288.6 ypg) on 98-of-152 passing with 13 touchdowns compared to two interceptions this season.
• Isaac Brown has carried the ball 39 times for a team-high 362 yards on the ground and has found the end zone one time as a runner. He’s also tacked on 13 catches for 91 yards (18.2 per game) and one touchdown in the pass game.
• This season, Keyjuan Brown has carried the ball 27 times for 160 yards (32 per game) and two touchdowns.
• Ja’Corey Brooks’ leads his squad with 489 yards as a receiver. He’s racked up that yardage on 25 catches (out of 37 targets) and scored six touchdowns.
• Chris Bell has put together a 195-yard season so far with two touchdowns, hauling in 11 passes on 19 targets.
• Jamari Johnson has a total of 121 receiving yards so far this year, grabbing nine throws.
• Tramel Logan has racked up three sacks to lead the team, while also picking up two TFL and five tackles.
• Stanquan Clark is the team’s tackle leader this year. He’s racked up 22 tackles and two TFL.
• Quincy Riley has a team-high one interception to go along with one pass defended.

Virginia Cavaliers

• Anthony Colandrea leads Virginia with 1,211 yards on 99-of-149 passing with eight touchdowns compared to four interceptions this season. He has chipped in with 158 rushing yards (31.6 ypg) on 49 carries while scoring two touchdowns on the ground.
• Xavier Brown has rushed 38 times for 315 yards.
• Kobe Pace has compiled 293 yards on 61 carries with two touchdowns, while also catching 11 passes for 114 yards.
• Malachi Fields has totaled 28 catches this season and his team-high yardage total sits at 412 (82.4 yards per game). He’s been targeted 42 times and has three touchdowns.
• Trell Harris has put up a 201-yard season so far with two touchdowns. He’s caught 13 passes on 18 targets.
• Tyler Neville has racked up 197 reciving yards (39.4 ypg) and two touchdowns this season.
• Kameron Butler has two sacks to lead the team, and also has one TFL and 14 tackles.
• Antonio Clary is the team’s top-tackler this year. He’s amassed 30 tackles, one TFL, one sack, and one interception.
• Chico Bennett Jr. has picked off a team-leading one pass. He also has 10 tackles, three TFL, one sack, and one pass defended to his name.