The No. 3 LSU Tigers (2-0) and the Florida Gators (1-1) play on Saturday, September 13, 2025 at Tiger Stadium in a battle of SEC opponents.

The Gators are underdogs, but by less than a touchdown (+6.5), versus the Tigers (with an over/under of 47.5 points).

Keep reading to check out our preview for this this matchup between the Tigers and the Gators, and uncover all of our betting picks here, too!

LSU vs. Florida betting lines

• Spread favorite: Tigers (-6.5)
• Moneyline: Tigers (-211), Gators (+174)
• Total: 47.5 points
• TV Channel: ESPN 4K
• Live Stream: Fubo

LSU vs. Florida betting info and stats

LSU, through two games with a spread so far this season, is 1-1-0 against the spread. LSU has yet to cover the spread when playing as favorites by at least 6.5 points (a 0-1 ATS record). LSU won the only game it played when favored on the moneyline this season. Florida, through two games with a set spread so far this season, has gone 1-1-0 against the spread. This is the first time on the year Florida is an underdog on the moneyline.

LSU vs. Florida key players

LSU Tigers

• Garrett Nussmeier has 467 passing yards for LSU, completing 68.4% of his passes and recording two touchdowns and one interception this season.
• Caden Durham has carried the ball 30 times for a team-high 103 yards on the ground and has found the end zone two times as a runner. He’s also tacked on five catches for 32 yards (16 per game).
• Zavion Thomas has 54 receiving yards (27 per game) on five catches, while also racking up 40 rush yards per game.
• Aaron Anderson’s team-high 172 yards as a receiver have come on 14 catches (out of 18 targets).
• Barion Brown has hauled in 13 receptions totaling 119 yards so far this campaign.
• Harold Perkins has collected one sack to pace the team, while also recording one TFL and seven tackles.
• West Weeks, LSU’s tackle leader, has 13 tackles and 0.5 sacks this year.
• Mansoor Delane has a team-high one interception to go along with three tackles and one pass defended.

Florida Gators

• DJ Lagway has 342 passing yards, or 171 per game, so far this season. He has completed 74.5% of his passes and has thrown four touchdowns with one interception.
• The team’s top rusher, Jadan Baugh, has carried the ball 27 times for 197 yards (98.5 per game) with one touchdown.
• Ja’Kobi Jackson has run for 46 yards across 13 attempts. He’s chipped in with two catches for 24 yards.
• Vernell Brown III has totaled eight receptions this season and his team-high yardage total sits at 135 (67.5 yards per game). He’s been targeted 11 times.
• Hayden Hansen has six receptions (on eight targets) for a total of 67 yards (33.5 yards per game) and one touchdown this year.
• Eugene Wilson III has racked up 56 reciving yards (28 ypg) and two touchdowns this season.
• Tyreak Sapp paces the team with one sack, and also has two TFL and five tackles.
• Florida’s leading tackler, Myles Graham, has 12 tackles and one TFL this year.