The Louisiana Tech Bulldogs (1-0) visit the No. 3 LSU Tigers (1-0) at Tiger Stadium on Saturday, September 6, 2025.

The Tigers are expected to come out on top by at least two touchdowns (currently -36.5) versus the Bulldogs. The over/under for this game is 49.5 points.

Keep reading for our preview for this this matchup between the Tigers and the Bulldogs, and uncover all of our betting picks here, too!

LSU vs. Louisiana Tech betting lines

• Spread favorite: Tigers (-36.5)
• Moneyline: Tigers (-11111), Bulldogs (+1650)
• Total: 49.5 points

LSU vs. Louisiana Tech betting info and stats

LSU has won just one game against the spread so far this season (1-0-0). LSU has yet to play a game as a moneyline favorite. Louisiana Tech has won once against the spread this season (1-0-0). This is the first time on the year Louisiana Tech is the moneyline underdog.

LSU vs. Louisiana Tech key players

LSU Tigers

• Garrett Nussmeier’s previous season stat line: 4,039 passing yards (310.7 per game), 336-for-524 (64.1%), 29 touchdowns and 12 picks.
• Last season Caden Durham took 138 carries for 754 yards (58 per game) and scored six touchdowns. When it comes to receiving, he also caught 28 passes for 260 yards (20 per game) and collected two TDs.
• Josh Williams ran for 482 yards on 117 carries (37.1 yards per game), with six rushing touchdowns last year. He also made his name known on the passing side with 31 receptions for 263 yards (20.2 per game).
• Aaron Anderson amassed 61 receptions for 875 yards and five touchdowns last season. He was targeted 88 times, and averaged 67.3 yards per game.
• Kyren Lacy also impressed receiving last year. He collected 58 receptions for 866 yards and nine touchdowns. He was targeted 106 times.
• Mason Taylor’s stat line last season: 546 receiving yards, 55 catches, two touchdowns, on 83 targets.
• Bradyn Swinson did his thing last season with an incredible stat line of 8.5 sacks, nine TFL and 46 tackles.
• Whit Weeks was a wrecking ball on the field, collecting 66 tackles, four TFL, 3.5 sacks, and one interception last year.
• Zy Alexander collected two interceptions while adding 24 tackles, one TFL, one sack, and two passes defended last year.

Louisiana Tech Bulldogs

• Evan Bullock completed 65.7% of his passes to throw for 2,102 yards and 14 touchdowns last season.
• Omiri Wiggins averaged 40.3 rushing yards per game and scored four rushing touchdowns.
• Amani Givens rushed for 319 yards and two touchdowns last season.
• Tru Edwards was targeted 8.5 times per game and collected 975 receiving yards and six touchdowns over the course of 2024.
• Jimmy Holiday caught 39 passes last season on his way to 476 yards and two receiving touchdowns.
• Eli Finley averaged 26.2 receiving yards per game on 3.2 targets per game a season ago.
• Last year David Blay collected six sacks, seven TFL and 34 tackles.
• Zach Zimos had an impactful defensive performance last season with 69 tackles, six TFL, and 0.5 sacks.
• A year ago Jacob Fields tallied 42 tackles, five TFL, and two passes defended as well as two interceptions.