The No. 11 LSU Tigers (4-1) host an SEC battle against the South Carolina Gamecocks (3-2) on Saturday, October 11, 2025 at Tiger Stadium.

The Tigers are solid favorites (-8.5) in their game versus the Gamecocks, with the over/under at 44 points. (On the moneyline, the Tigers are -333 and the Gamecocks are +266.)

Below you’ll find our betting primer for this this game between the Tigers and the Gamecocks, and uncover all of our expert picks here, too!

LSU vs. South Carolina betting lines

• Spread favorite: Tigers (-8.5)
• Moneyline: Tigers (-333), Gamecocks (+266)
• Total: 44 points
• TV Channel: SEC Network
• Live Stream: Fubo

LSU vs. South Carolina betting info and stats

LSU has two wins against the spread this season (2-3-0). LSU has yet to cover the spread when favorites by at least 8.5 points (a 0-2 ATS record). LSU has won both games as the moneyline favorite this season. South Carolina is 3-2-0 against the spread so far this season. When South Carolina is an underdog by 8.5 points or more, it has posted a record of 1-0 ATS. South Carolina has played as an underdog on the moneyline once so far this season, and failed to pick up the victory.

LSU vs. South Carolina recent stats and trends

LSU Tigers

• LSU is 1-2 against the spread in its past three games, and has a 2-1 straight-up record in those contests.
• LSU and its opponents have hit the over one time in those games.
• LSU’s past three outings have ended with an average of 55.3 points scored. That’s 11.3 more points than this contest’s over/under.

South Carolina Gamecocks

• South Carolina has covered the spread twice in its past three contests while putting up a 2-1 record straight-up in those games.
• The final combined score of the past three South Carolina games has surpassed the set total two times.
• The last three South Carolina games averaged 48.2 total points, 4.2 more points than this matchup’s over/under.

LSU vs. South Carolina key players

LSU Tigers

• Garrett Nussmeier has thrown for 1,157 yards (231.4 ypg) to lead LSU, completing 67.3% of his passes and tossing seven touchdown passes compared to three interceptions this season.
• Caden Durham has racked up 213 yards on 52 carries while finding paydirt two times.
• Harlem Berry has racked up 109 yards on 22 attempts, scoring one time.
• Aaron Anderson’s team-high 305 yards as a receiver have come on 23 receptions (out of 34 targets).
• Barion Brown has reeled in 25 passes while averaging 47.8 yards per game and scoring one touchdown.
• Bauer Sharp has been the target of 22 passes and compiled 15 receptions for 179 yards, an average of 35.8 yards per contest. He’s found the end zone one time through the air this season.
• Damien Shanklin leads the team with 2.0 sacks, and also has 2.0 TFL.
• West Weeks, LSU’s leading tackler, has 24 tackles, 1.0 TFL, and 0.5 sacks this year.
• Dashawn Spears has a team-leading two interceptions to go along with two passes defended.

South Carolina Gamecocks

• LaNorris Sellers has thrown for 886 yards (177.2 yards per game) while completing 66.7% of his passes and collecting four touchdown passes with one interception this season. He’s also rushed for 98 yards with one touchdown.
• The team’s top rusher, Rahsul Faison, has carried the ball 41 times for 163 yards (32.6 per game) with three touchdowns.
• Oscar Adaway III has run for 119 yards across 32 attempts, scoring one touchdown.
• Vandrevius Jacobs has collected 18 receptions this season and his team-high yardage total sits at 323 (80.8 yards per game). He’s been targeted 20 times and has two touchdowns.
• Nyck Harbor has 11 receptions (on 20 targets) for a total of 220 yards (44.0 yards per game) and one touchdown this year.
• Donovan Murphree has racked up 94 reciving yards (23.5 ypg) this season.
• Dylan Stewart paces the team with 4.0 sacks, and also has 6.0 TFL and 21 tackles.
• Fred Johnson, South Carolina’s top tackler, has 24 tackles, 1.0 TFL, one sack, and one interception this year.
• Gerald Kilgore has a team-high two interceptions to go along with six tackles, 1.0 TFL, and two passes defended.