Week 4 action in the NFL features Matthew Stafford and the Los Angeles Rams hitting the field against the Indianapolis Colts at 4:05 p.m. ET on Sunday. Below we dig into Stafford’s stats and trends in relation to prop bets, helping you make good predictions for this matchup.

Matthew Stafford Prop Lines

• Matchup: Los Angeles Rams vs. Indianapolis Colts
• Time: 4:05 p.m. ET
• Date: September 28, 2025
• Passing yards prop: Over 252.5 (-112)

Matthew Stafford Stats and Trends

• Stafford has 739 yards passing (246.3 per game) and has completed 66.3% of his throws (63-for-95), with five TDs and two picks.
• Stafford throws for 246.3 yards per game. That’s 6.2 fewer yards than his over/under on Sunday.
• In three contests this year, Stafford has exceeded 252.5 passing yards on one occasion.
• His passing yards average of 246.3 yards is higher than his average prop total this year (235.8) by 10.5 yards.
• This year, Stafford has gone over his passing yards prop bet total twice.
• He has thrown for a touchdown in all three games this season, with more than one TD pass on two occasions.
• Stafford also has carried the ball six times for -8 yards, picking up -2.7 yards per game.

Recent Performances vs. the Colts

Rams Home Splits (Last Season)

• At home, the Rams scored 23.7 points per game and conceded 24.9. That is more than they scored (21.6) and allowed (22.7) overall.
• The Rams’ average yards gained (338.3) and allowed (360.2) at home were both higher than their overall averages of 331.4 and 353.1, respectively.
• The Rams’ average passing yards gained (237.8) and conceded (230) at home were both higher than their overall averages of 227.5 and 223.1, respectively.
• The Rams racked up 100.6 rushing yards per game at home (3.2 less than their overall average), and conceded 130.2 at home (0.2 more than overall).
• In home games, the Rams converted 39.3% of third downs and allowed 43.1% to be converted. That’s more than they converted (36.8%) and allowed (40.7%) overall.