The Boston College Eagles (1-0) visit the Michigan State Spartans (1-0) at Spartan Stadium on Saturday, September 6, 2025.

The Spartans are favored, but by less than a touchdown (-3.5), against the Eagles. The over/under for this game is 45.5 points.

Keep reading for our preview for this this contest between the Spartans and the Eagles, and uncover all of our betting picks here, too!

Michigan State vs. Boston College betting lines

• Spread favorite: Spartans (-3.5)
• Moneyline: Spartans (-171), Eagles (+142)
• Total: 45.5 points
• TV Channel: NBC Sports 4K
• Live Stream: Fubo

Michigan State vs. Boston College betting info and stats

Michigan State, through one game with a spread so far this season, is 0-1-0 against the spread. Michigan State has yet to cover the spread when serving as favorites by at least 3.5 points (a 0-1 ATS record). In one game as the moneyline favorite, Michigan State won. Boston College has yet to lose a game against the spread so far this season (1-0-0). This is the first game on the year Boston College is the moneyline underdog.

Michigan State vs. Boston College key players

Michigan State Spartans

• Aidan Chiles had a passing stat line last year of 2,415 yards with a 59.3% completion rate (192-for-324), 13 touchdowns, 12 interceptions, and an average of 201.3 yards per game. His rushing stat line was 96 carries for 234 yards and three TDs.
• Kay’Ron Lynch-Adams racked up 649 rushing yards (54.1 per game) and two touchdowns last year.
• Nate Carter put up 499 rushing yards on 116 carries and five touchdowns last season. He also made a mark receiving with 18 catches for 173 yards and two scores.
• Nick Marsh reeled in 41 catches for 649 yards (54.1 per game) while being targeted 63 times. He also scored three touchdowns.
• Montorie Foster Jr. also impressed receiving last year. He bagged 46 receptions for 588 yards and three touchdowns. He was targeted 86 times.
• Jack Velling hauled in 36 passes for 411 yards and one touchdown, putting up 34.3 yards per game last year.
• Last season Khris Bogle stacked up four sacks, six TFL and 29 tackles.
• Last season Jordan Turner averaged 54 tackles, eight TFL, three sacks, and two interceptions.
• Charles Brantley intercepted three passes last year while also totaling 26 tackles, one TFL, and three passes defended.

Boston College Eagles

• Thomas Castellanos completed 61.5% of his passes to throw for 1,366 yards and 18 touchdowns last season. Castellanos also helped with his legs, tallying one touchdown on 21.6 yards per game.
• Kye Robichaux averaged 57.2 rushing yards and scored 10 rushing touchdowns.
• Treshaun Ward ran for two touchdowns on 406 yards a year ago. Ward also was productive as a receiver, totaling 15 receptions for 268 yards with four touchdowns.
• Lewis Bond averaged 53 receiving yards and collected three receiving touchdowns over the course of the 2024 season.
• Reed Harris averaged 37.4 receiving yards on 3.3 targets per game in 2024, scoring four touchdowns.
• Kamari Morales averaged 27.1 receiving yards per game on 2.8 targets per game a season ago.
• Last year Donovan Ezeiruaku collected 15.5 sacks, 15 TFL and 73 tackles.
• KP Price had an impressive defensive performance last season with 73 tackles, two TFL, one sack, and two interceptions.
• Carter Davis came up with three interceptions in addition to 45 tackles and three passes defended a year ago.