The Northern Illinois Huskies (1-1) visit the Mississippi State Bulldogs (3-0) at Davis Wade Stadium at Scott Field on Saturday, September 20, 2025.

The Bulldogs are expected to come out on top by at least two touchdowns (currently -23.5) against the Huskies. The over/under for this matchup is 48.5 points.

Below you can find our betting primer for this this contest between the Bulldogs and the Huskies, and uncover all of our predictions here, too!

Mississippi State vs. Northern Illinois betting lines

• Spread favorite: Bulldogs (-23.5)
• Moneyline: Bulldogs (-2500), Huskies (+1150)
• Total: 48.5 points
• TV Channel: SEC Network
• Live Stream: Fubo

Mississippi State vs. Northern Illinois betting info and stats

Mississippi State is 3-0-0 against the spread through three opportunities this season. Mississippi State has always covered the spread when playing as favorites by at least 23.5 points (a 1-0 ATS record). Mississippi State has won both games as the moneyline favorite this season. Northern Illinois, in two games with a set spread this season, is 1-1-0 against the spread. Northern Illinois has played a game as an underdog on the moneyline once this season, and failed to pick up the victory.

Mississippi State vs. Northern Illinois key players

Mississippi State Bulldogs

• Blake Shapen has 722 passing yards for Mississippi State, completing 67.9% of his passes and recording six touchdowns and two interceptions this season.
• Da’Marion Bothwell has carried the ball 30 times for a team-high 170 yards on the ground and has found the end zone four times as a runner.
• Davon Booth has carried the ball 27 times for 126 yards (42.0 per game) and one touchdown.
• Brenen Thompson’s 278 yards as a receiver lead the team. He’s been targeted 21 times and has registered 15 receptions and three touchdowns.
• Anthony Evans III has hauled in 17 receptions totaling 210 yards, finding the end zone two times as a receiver so far this campaign.
• Jordan Mosley has a total of 94 receiving yards so far this year, grabbing three throws and scoring one touchdown.
• Will Whitson has 2.0 sacks to lead the team, and also has 4.0 TFL and seven tackles.
• Isaac Smith is the team’s leading tackler this year. He’s picked up 16 tackles.
• Jayven Williams leads the team with one interception, while also collecting three tackles and one pass defended.

Northern Illinois Huskies

• Josh Holst leads Northern Illinois with 192 yards on 26-of-40 passing with zero touchdowns compared to one interception this season.
• Chavon Wright has run the ball 38 times for 167 yards, with one touchdown.
• Telly Johnson Jr. has collected 153 yards (on 31 carries) with one touchdown.
• DeAree Rogers has racked up 89 receiving yards on 10 catches to pace his team so far this season.
• Gary Givens III has caught two passes and compiled 26 receiving yards (13.0 per game).
• Jaylen Poe’s six targets have resulted in five grabs for 24 yards.
• Roy Williams leads the team with 1.0 sack, and also has 1.0 TFL and six tackles.
• Quinton Urwiler is the team’s top-tackler this year. He’s racked up 20 tackles and 0.5 sacks.
• Muhammad Jammeh leads the team with one interception, while also recording 11 tackles and one pass defended.