The Missouri Tigers (6-3) square off against a fellow SEC opponent when they host the Mississippi State Bulldogs (5-5) on Saturday, November 15, 2025 at Memorial Stadium/Faurot Field.

The Tigers are the favorites (-6.5) in their matchup against the Bulldogs, with the over/under being 51.5 points. (On the moneyline, the Tigers are -262 and the Bulldogs are +212.)

Keep reading for our betting primer for this this contest between the Tigers and the Bulldogs, and uncover all of our betting picks here, too!

Missouri vs. Mississippi State betting lines

• Spread favorite: Tigers (-6.5)
• Moneyline: Tigers (-262), Bulldogs (+212)
• Total: 51.5 points
• TV Channel: SEC Network
• Live Stream: Fubo

Missouri vs. Mississippi State betting info and stats

Missouri is 5-4-0 against the spread in nine opportunities so far this season. Missouri is 2-2 ATS when favored by at least 6.5 points. In the five games favored on the moneyline, Missouri has recorded a 5-0 record. Mississippi State has an 8-2-0 record against the spread this season. Mississippi State’s record against the spread is 4-2 in games it was set as the underdog by 6.5 points or more. Mississippi State has a 2-5 record this year in games it hs played as the moneyline underdog.

Missouri vs. Mississippi State recent stats and trends

Missouri Tigers

• Missouri has covered the spread once in its past three matchups while putting together a 1-2 record straight-up in those games.
• Missouri and its opponents have combined to hit the over once in those games.
• The last three Missouri games averaged 48.3 total points, 3.2 fewer points than this matchup’s point total.

Mississippi State Bulldogs

• Mississippi State is 2-1 against the spread and 1-2 overall in its last three contests.
• The final combined score of the past three Mississippi State games has exceeded the set total each time.
• The last three Mississippi State games averaged 57.2 total points, 5.7 more points than this matchup’s over/under.

Missouri vs. Mississippi State key players

Missouri Tigers

• Beau Pribula has compiled 1,690 yards (211.3 ypg) on 158-of-227 passing with 11 touchdowns compared to seven interceptions this season. In addition, he’s added 220 rushing yards (27.5 ypg) on 71 carries while scoring five touchdowns on the ground.
• Ahmad Hardy has carried the ball 172 times for a team-high 1,046 yards on the ground and has found the end zone 12 times as a runner.
• Jamal Roberts has been handed the ball 83 times this year and racked up 538 yards (59.8 per game) with four touchdowns.
• Kevin Coleman Jr.’s 559 yards as a receiver lead the team. He’s been targeted 64 times and has totaled 52 receptions and one touchdown.
• Marquis Johnson has caught 28 passes for 345 yards (38.3 yards per game) and two touchdowns this year.
• Donovan Olugbode has compiled 20 catches for 287 yards, an average of 31.9 yards per game. He’s scored one time as a receiver this season.
• Damon Wilson Jr. paces the team with 6.0 sacks, and also has 5.0 TFL, 13 tackles, and one interception.
• Josiah Trotter is the team’s leading tackler this year. He’s picked up 58 tackles, 7.0 TFL, and one sack.
• Santana Banner has a team-leading one interception to go along with 32 tackles, 1.0 TFL, and one pass defended.

Mississippi State Bulldogs

• Blake Shapen has racked up 2,237 yards (223.7 yards per game) while completing 64.9% of his passes and recording 15 touchdown passes with six interceptions this season.
• Da’Marion Bothwell has rushed for 534 yards on 105 carries so far this year while scoring six times on the ground.
• Davon Booth has racked up 512 yards (on 123 attempts) with seven touchdowns, while also catching 11 passes for 143 yards and two touchdowns.
• Brenen Thompson has registered 45 receptions this season and his team-high yardage total sits at 808 (80.8 yards per game). He’s been targeted 69 times and has six touchdowns.
• Anthony Evans III has caught 56 passes and compiled 680 receiving yards (68.0 per game) with four touchdowns.
• Seydou Traore’s 27 grabs (on 42 targets) have netted him 265 yards (26.5 ypg) and four touchdowns.
• Will Whitson leads the team with 2.0 sacks, and also has 4.0 TFL and seven tackles.
• Jahron Manning is the team’s tackle leader this year. He’s totaled 69 tackles, 3.0 TFL, and one interception.
• Brylan Lanier leads the team with three interceptions, while also recording 51 tackles, 2.0 TFL, one sack, and three passes defended.