The Northwestern Wildcats (5-5) and the Minnesota Golden Gophers (6-4) play on Saturday, November 22, 2025 at Wrigley Field in a clash of Big Ten opponents.

The Wildcats are favored, but by less than a touchdown (-3.5), versus the Golden Gophers. The over/under for this game is 40.5 points.

Keep reading to check out our betting primer for this this game between the Wildcats and the Golden Gophers, and discover all of our expert picks here, too!

Northwestern vs. Minnesota betting lines

• Spread favorite: Wildcats (-3.5)
• Moneyline: Wildcats (-181), Golden Gophers (+151)
• Total: 40.5 points
• TV Channel: Big Ten Network
• Live Stream: Fubo

Northwestern vs. Minnesota betting info and stats

Northwestern has six wins against the spread so far this season (6-3-1). Northwestern has covered the spread three times in games it was favored by at least 3.5 points (a 3-1 ATS record). Northwestern has been listed the moneyline favorite four times this season, and has recorded a 4-0 record in those matchups. Minnesota, through 10 games with a set spread so far this season, has gone 2-8-0 against the spread. In the four games Minnesota has been an underdog by at least 3.5 points, it covered the spread one time. This will be the fifth time this year Minnesota is an underdog on the moneyline and has gone 1-3 in such contests.

Northwestern vs. Minnesota recent stats and trends

Northwestern Wildcats

• Northwestern has covered the spread once in its past three contests while putting up a 0-3 record straight-up in those games.
• The final combined score of the past three Northwestern games has exceeded the set total each time.
• The last three Northwestern games averaged 46.5 total points, 6.0 more points than this matchup’s point total.

Minnesota Golden Gophers

• Minnesota is winless against the spread in its past three games, and has a 0-3 straight-up record in those contest.
• Minnesota and its opponents have hit the over twice in those games.
• The last three Minnesota games averaged 43.2 total points, 2.7 more points than this matchup’s point total.

Northwestern vs. Minnesota key players

Northwestern Wildcats

• Preston Stone has recorded 1,706 yards (170.6 ypg) on 159-of-273 passing with 11 touchdowns compared to nine interceptions this season.
• Caleb Komolafe has carried the ball 153 times for a team-high 757 yards on the ground and has found the end zone nine times as a runner.
• Joseph Himon II has been handed the ball 90 times this year and racked up 428 yards (47.6 per game).
• Griffin Wilde’s team-high 644 yards as a receiver have come on 45 receptions (out of 77 targets) with five touchdowns.
• Hayden Eligon II has caught 19 passes for 250 yards (27.8 yards per game) and two touchdowns this year.
• Hunter Welcing has been the target of 32 passes and hauled in 20 receptions for 239 yards, an average of 23.9 yards per contest. He’s found the end zone two times through the air this season.
• Aidan Hubbard has 4.5 sacks to pace the team, and also has 6.0 TFL and 24 tackles.
• Robert Fitzgerald is the team’s top-tackler this year. He’s amassed 83 tackles, 4.0 TFL, and one interception.
• Mac Uihlein has picked off a team-leading four passes. He also has 70 tackles, 4.0 TFL, and four passes defended to his name.

Minnesota Golden Gophers

• Drake Lindsey leads Minnesota with 1,881 yards on 190-of-307 passing with 11 touchdowns compared to six interceptions this season.
• Darius Taylor has rushed for 411 yards on 90 carries so far this year while scoring one time on the ground. He’s also added 20 catches, totaling 174 yards.
• Fame Ijeboi has collected 393 yards (on 85 carries) with two touchdowns.
• Lemeke Brockington’s 417 receiving yards (46.3 yards per game) are best on his team. He has 40 receptions on 56 targets with three touchdowns.
• Javon Tracy has put together a 343-yard season so far with three touchdowns. He’s caught 28 passes on 48 targets.
• Jalen Smith has racked up 327 reciving yards (40.9 ypg) and two touchdowns this season.
• Anthony Smith leads the team with 9.5 sacks, and also has 8.0 TFL and 27 tackles.
• Minnesota’s tackle leader, Devon Williams, has 71 tackles, 5.0 TFL, and 2.5 sacks this year.
• John Nestor has picked off a team-high three passes. He also has 39 tackles, 4.0 TFL, and three passes defended to his name.