MAC opponents meet when the Ohio Bobcats (7-4) and the Buffalo Bulls (5-6) square off on Friday, November 28, 2025 at UB Stadium.

The Bobcats are solid favorites (-7) in their game against the Bulls, with the over/under being 44.5 points. (On the moneyline, the Bobcats are -271 and the Bulls are +219.)

Keep reading for our preview for this this matchup between the Bobcats and the Bulls, and find all of our predictions here, too!

Ohio vs. Buffalo betting lines

• Spread favorite: Bobcats (-7)
• Moneyline: Bobcats (-271), Bulls (+219)
• Total: 44.5 points
• TV Channel: ESPN U
• Live Stream: Fubo

Ohio vs. Buffalo betting info and stats

Ohio is 6-5-0 against the spread in 11 opportunities this season. Ohio has covered the spread two times when the favorite by at least 7 points (a 2-4 ATS record). Ohio has won six of its seven games played when favored on the moneyline this season. Buffalo has a 3-7-1 record against the spread so far this season. When Buffalo is an underdog by 7 points or more, it has gone 1-0 ATS. This is the sixth time this year Buffalo is an underdog on the moneyline and has gone 1-4 in such contests.

Ohio vs. Buffalo recent stats and trends

Ohio Bobcats

• Ohio is 1-2 against the spread over its last three games, and has a 2-1 straight-up record in those contests.
• In one of those three games, the final combined score surpassed the set total.
• Ohio’s last three games have ended with an average of 50.2 points scored. That’s 5.7 more points than this contest’s over/under.

Buffalo Bulls

• Buffalo is 1-2 against the spread and 2-1 overall over its past three games.
• Two times in those three games, the final combined score has gone over the set total.
• The last three Buffalo games averaged 42.2 total points, 2.3 fewer points than this matchup’s point total.

Ohio vs. Buffalo key players

Ohio Bobcats

• Parker Navarro has been a dual threat for Ohio so far this season. He has 2,085 passing yards, completing 63% of his passes and recording 12 touchdown passes and nine interceptions this season. He’s rushed for 722 yards (65.6 ypg) on 131 carries with seven rushing touchdowns.
• Sieh Bangura has 1,123 rushing yards on 199 carries with 13 touchdowns.
• Chase Hendricks’ 858 yards as a receiver lead the team. He’s been targeted 98 times and has registered 62 receptions and six touchdowns.
• Rodney Harris II has reeled in 25 passes while averaging 36.4 yards per game and scoring two touchdowns.
• Mason Williams’ 23 receptions are good enough for 253 yards and two touchdowns.
• Jay Crable has collected 5.0 sacks to pace the team, while also picking up 6.0 TFL and 21 tackles.
• Adonis Williams Jr. is the team’s leading tackler this year. He’s collected 58 tackles and 2.0 TFL.
• Tank Pearson has picked off a team-leading two passes. He also has 37 tackles and two passes defended to his name.

Buffalo Bulls

• Ta’Quan Roberson has put up 2,250 passing yards, or 225.0 per game, so far this season. He has completed 57.6% of his passes and has recorded 15 touchdowns with 11 interceptions. He’s also contributed on the ground with 12.1 rushing yards per game while scoring as a runner two times.
• Al-Jay Henderson has rushed 177 times for 724 yards, with five touchdowns. He’s also tacked on 25 catches for 181 yards and one touchdown.
• Lamar Sperling has racked up 37 carries and totaled 221 yards with one touchdown.
• Nik McMillan has registered 56 receptions this season and his team-high yardage total sits at 853 (77.5 yards per game). He’s been targeted 91 times and has three touchdowns.
• Victor Snow has put together a 733-yard season so far with eight touchdowns. He’s caught 58 passes on 83 targets.
• Jasaiah Gathings’ 73 targets have resulted in 34 catches for 380 yards and two touchdowns.
• Junior Poyser has collected 5.0 sacks to pace the team, while also recording 4.0 TFL and 23 tackles.
• Khalil Murdock, Buffalo’s leading tackler, has 95 tackles, 7.0 TFL, and 4.5 sacks this year.
• Mitchell Gonser leads the team with two interceptions, while also collecting 45 tackles, 2.0 TFL, one sack, and two passes defended.