SEC foes meet when the No. 6 Ole Miss Rebels (10-1) and the Mississippi State Bulldogs (5-6) square off on Friday, November 28, 2025 at Davis Wade Stadium at Scott Field.

The Rebels are solid favorites (-7) in their matchup against the Bulldogs, with the over/under at 63 points. (On the moneyline, the Rebels are -287 and the Bulldogs are +232.)

Read on for our preview for this this contest between the Rebels and the Bulldogs, and find all of our expert predictions here, too!

Ole Miss vs. Mississippi State betting lines

• Spread favorite: Rebels (-7)
• Moneyline: Rebels (-287), Bulldogs (+232)
• Total: 63 points
• TV Channel: ABC (WLS – Chicago, IL)
• Live Stream: Fubo

Ole Miss vs. Mississippi State betting info and stats

Ole Miss has an against-the-spread record of 6-5-0 this season. Ole Miss has an ATS record of 3-4 this season when the favorite by 7 points or more. Ole Miss has won eight of its eight games played when favored on the moneyline this season. Mississippi State has eight wins against the spread in 11 opportunities this season (8-3-0). In the five games Mississippi State has been the underdog by at least 7 points, it covered the spread three times (3-2). Mississippi State has been an underdog on the moneyline eight times this year, going 2-6 in those games.

Ole Miss vs. Mississippi State recent stats and trends

Ole Miss Rebels

• Ole Miss is 1-2 against the spread over its past three games, and has a 3-0 straight-up record in those matchups.
• One time in those three games, the final combined score exceeded the set total.
• The last three Ole Miss games averaged 57.5 total points, 5.5 fewer points than this matchup’s over/under.

Mississippi State Bulldogs

• Mississippi State is 1-2 against the spread and 3-0 overall during its past three matchups.
• Mississippi State and its opponents have hit the over all three times in those games.
• The last three Mississippi State games averaged 58.2 total points, 4.8 fewer points than this matchup’s over/under.

Ole Miss vs. Mississippi State key players

Ole Miss Rebels

• Trinidad Chambliss has thrown for 2,657 yards, completing 65.2% of his passes and recording 14 touchdowns and three interceptions this season. He’s also run for 444 yards (40.4 ypg) on 110 carries with six rushing touchdowns.
• The team’s top rusher, Kewan Lacy, has carried the ball 231 times for 1,136 yards (103.3 per game), scoring 19 times.
• Harrison Wallace III’s team-leading 647 yards as a receiver have come on 42 receptions (out of 70 targets) with two touchdowns.
• Dae’Quan Wright has caught 28 passes for 485 yards (44.1 yards per game) and four touchdowns this year.
• Deuce Alexander’s 32 receptions have yielded 483 yards and one touchdown.
• Princewill Umanmielen leads the team with 5.5 sacks, and also has 6.0 TFL and 31 tackles.
• T.J. Dudley, Ole Miss’ top tackler, has 64 tackles, 2.0 TFL, and 0.5 sacks this year.
• Wydett Williams Jr. has picked off a team-high three passes. He also has 44 tackles and three passes defended to his name.

Mississippi State Bulldogs

• Blake Shapen has compiled 2,436 yards (221.5 ypg) while completing 64.1% of his passes and tossing 15 touchdown passes with eight interceptions this season.
• Da’Marion Bothwell is his team’s leading rusher with 111 carries for 559 yards, or 62.1 per game. He’s found the end zone six times on the ground, as well.
• Davon Booth has collected 546 yards (on 133 attempts) with seven touchdowns, while also grabbing 14 passes for 158 yards and two touchdowns.
• Brenen Thompson has hauled in 868 receiving yards on 47 catches to pace his team so far this season while scoring six touchdowns as a receiver.
• Anthony Evans III has 63 receptions (on 91 targets) for a total of 751 yards (68.3 yards per game) and four touchdowns this year.
• Seydou Traore’s 47 targets have resulted in 30 receptions for 294 yards and five touchdowns.
• Nic Mitchell has collected 2.5 sacks to lead the team, while also picking up 4.0 TFL, 64 tackles, and one interception.
• Jahron Manning, Mississippi State’s tackle leader, has 75 tackles, 3.0 TFL, and one interception this year.
• Brylan Lanier leads the team with three interceptions, while also recording 57 tackles, 2.0 TFL, one sack, and three passes defended.