The No. 7 Penn State Nittany Lions (3-1) meet a conference opponent when they visit the UCLA Bruins (0-4) on Saturday, October 4, 2025 at the Rose Bowl in a Big Ten battle.

The Nittany Lions are very heavy favorites (currently -24.5) in their game versus the Bruins, with the over/under being 48.5 points. (On the moneyline, the Nittany Lions are -2703 and the Bruins are +1275.)

Keep reading for our betting primer for this this game between the Nittany Lions and the Bruins, and uncover all of our predictions here, too!

Penn State vs. UCLA betting lines

• Spread favorite: Nittany Lions (-24.5)
• Moneyline: Nittany Lions (-2703), Bruins (+1275)
• Total: 48.5 points
• TV Channel: CBS (KBAK-Bakersfield, CA)
• Live Stream: Fubo

Penn State vs. UCLA betting info and stats

Penn State, in four games with a spread this season, is 0-4-0 against the spread. Penn State has yet to cover the spread when favorites by at least 24.5 points (a 0-3 ATS record). Penn State has split them games as a moneyline favorite this season. UCLA has won just one game against the spread this season (1-3-0). This is the third game this year UCLA is the moneyline underdog, after losing the previous two such games.

Penn State vs. UCLA recent stats and trends

Penn State Nittany Lions

UCLA Bruins

Penn State vs. UCLA key players

Penn State Nittany Lions

• Drew Allar has racked up 763 yards (190.8 ypg) on 71-of-113 passing with six touchdowns compared to two interceptions this season. In addition, he’s added 69 rushing yards (17.3 ypg) on 19 carries.
• The team’s top rusher, Kaytron Allen, has carried the ball 46 times for 327 yards (81.8 per game), scoring four times.
• Nicholas Singleton has been handed the ball 52 times this year and racked up 200 yards (50.0 per game) with five touchdowns. He’s also helped out in the pass game with eight grabs for 73 yards
• Trebor Pena’s 182 yards as a receiver pace the team. He’s been targeted 22 times and has registered 15 receptions and one touchdown.
• Kyron Ware-Hudson has caught 14 passes while averaging 39.0 yards per game and scoring one touchdown.
• Luke Reynolds’ 14 receptions have yielded 151 yards.
• Tony Rojas has 2.0 sacks to pace the team, and also has 4.0 TFL and 24 tackles.
• Penn State’s top-tackler, Amare Campbell, has 36 tackles, 3.0 TFL, and one sack this year.
• Elliot Washington II has a team-leading one interception to go along with four tackles and one pass defended.

UCLA Bruins

• Nico Iamaleava has thrown for 788 yards (197.0 ypg) to lead UCLA, completing 65.3% of his passes and tossing four touchdown passes and three interceptions this season. He is also a playmaker on the ground, racking up 204 yards (51.0 ypg) on 44 carries with one touchdown.
• Anthony Woods has 103 receiving yards (25.8 ypg) on 13 catches and one touchdown while collecting 127 rushing yards on 25 attempts.
• Kwazi Gilmer has registered 19 receptions this season and his team-high yardage total sits at 225 (56.3 yards per game). He’s been targeted 33 times and has one touchdown.
• Mikey Matthews has 10 receptions (on 18 targets) for a total of 123 yards (41.0 yards per game) this year.
• Anthony Jones has collected 1.5 sacks to pace the team, while also picking up 2.0 TFL and nine tackles.
• JonJon Vaughns is the team’s tackle leader this year. He’s totaled 38 tackles and 1.0 TFL.