Phillies vs. Padres Betting Lines, Odds, & Player Matchups May 25, 2026

Data Skrive

The San Diego Padres (31-21) host the Philadelphia Phillies (26-27) on Monday at 6:40 p.m. ET. The Padres are underdogs (+110) against the favored Phillies (-132). Jesus Luzardo starts for Philadelphia while San Diego will counter with Randy Vasquez.

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Betting Odds

Phillies to win vs Padres -132

Bet $20, Payout $35.15

Phillies vs. Padres betting lines

  • Favorite: Phillies (-132)
  • Underdog: Padres (+110)
  • Over/under: 7.5

Phillies betting info, hitting leaders, & pitching

Phillies betting info

  • The Phillies have been favored on the moneyline 38 total times this season. They’ve finished 21-17 in those games.
  • Philadelphia has gone 17-15 (winning 53.1% of its games) when it has played as moneyline favorites of -132 or shorter.
  • The Phillies have an implied moneyline win probability of 56.9% in this matchup.
  • In the 53 games in which oddsmakers have set an over/under for Philadelphia, it has combined with opponents to go over the total 24 times (24-27-2).
  • The Phillies have a 17-36-0 record ATS this season (covering only 32.1% of the time).

Phillies hitting info

  • Bryce Harper is batting .274 with 10 doubles, a triple, 12 home runs and 28 walks.
  • Harper’s home runs rank 16th in MLB and he ranks 21st in RBI in MLB.
  • Kyle Schwarber’s 20 home runs and 36 runs batted in both lead his team.
  • Schwarber ranks first in home runs and 10th in RBI among MLB hitters this season.
  • Brandon Marsh paces the Phillies with a .320 batting average.
  • Bryson Stott has eight doubles, two triples, five home runs and 10 walks while hitting .239.
  • Stott takes a seven-game hitting streak into this matchup. During his last 10 outings he is hitting .324 with two doubles, two home runs, three walks and nine RBIs.

Phillies pitching rankings

  • The 9.5 strikeouts per nine innings compiled by the Phillies pitching staff ranks second in MLB.
  • Philadelphia has a 4.14 team ERA that ranks 17th among all MLB pitching staffs.
  • The Phillies average MLB’s 19th-ranked WHIP (1.327).
  • Phillies pitchers combine to give up the 10th-fewest home runs in baseball (50 total, 0.9 per game).
  • Philadelphia its 3-1 loss the last time out, the team struck out five Guardians batters while allowing nine hits.

Padres betting info, hitting leaders, & pitching

Padres betting info

  • The Padres have won 14, or 58.3%, of the 24 games they’ve played as underdogs this season.
  • San Diego has entered 16 games this season as the underdog by +110 or more and is 10-6 in those contests.
  • The moneyline for this contest implies a 47.6% chance of a victory for the Padres.
  • So far this season, San Diego and its opponents have hit the over in 22 of its 52 games with a total.
  • In 52 games with a spread this season, the Padres are 30-22-0 ATS.

Padres hitting info

  • Xander Bogaerts is batting .250 with seven home runs and 24 RBI for San Diego this season.
  • Bogaerts’ home run total ranks 56th in the big leagues, and he is 83rd in RBI.
  • Gavin Sheets is batting .253 this season with nine home runs and 23 RBI.
  • Sheets currently ranks 40th in homers and 94th in RBI in the big leagues.
  • Sheets heads into this game on a four-game hitting streak. In his last five games he is batting .235 with two walks and two RBIs.
  • Manny Machado leads San Diego in runs batted in (25) this season. He has a .174 batting average and a .337 slugging percentage.
  • Miguel Andujar is batting .280 with an OBP of .303 and a slugging percentage of .487 this season.

Padres pitching rankings

  • The Padres have an 8.8 K/9 this season as a pitching staff, ninth-best in baseball.
  • San Diego has the 12th-ranked ERA (3.86) in the majors this season.
  • Padres pitchers have a 1.263 WHIP this season, 13th in the majors.
  • With just 42 homers allowed, the Padres rank third in the league at preventing long balls.
  • San Diego pitchers struck out 11 Athletics hitters while allowing 10 base hits in a 5-2 loss its last time out.
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Ryan Knuppel

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About Ryan Knuppel

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Betting Guide

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