Pirates vs. Athletics Betting Lines, Odds, & Player Matchups September 21, 2025

Data Skrive
Data Skrive

The Pittsburgh Pirates (66-89) host the Athletics (73-82) on Sunday at PNC Park, starting at 1:35 p.m. ET. The Pirates are favored on the moneyline (-112), while the Athletics are -107 underdogs, even though they are favored against the spread (1.5) with +154 odds. Mike Burrows starts for Pittsburgh while Sacramento will counter with Mitch Spence.

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Money Line

Pirates to win vs Athletics -112

Bet $20, Payout $37.86

Pirates vs. Athletics betting lines

  • Favorite: Pirates (-112)
  • Underdog: Athletics (-107)
  • Over/under: 8.5

Pirates betting info, hitting leaders, & pitching

Pirates betting info

  • The Pirates have won 47.7% of the games this season when they were the moneyline favorite (21-23).
  • The Pirates have gone 21-20 in games they have played as a moneyline favorite with odds of -112 or shorter (51.2%).
  • The Pirates have an implied moneyline win probability of 52.8% in this contest.
  • The Pirates have combined with their opponents to hit the over on the total 62 times this season for a 62-87-5 record against the over/under.
  • The Pirates have an 82-72-0 record against the spread this season (covering 53.2% of the time).

Pirates hitting info

  • Bryan Reynolds leads the Pirates in runs batted in (73) and has accumulated a team-high batting average of .243.
  • In MLB action, Reynolds ranks 121st in home runs and 69th in RBI.
  • Reynolds has safely hit in two straight games. During his last five outings he is batting .222 with a double, a home run, three walks and two RBIs.
  • Andrew McCutchen is hitting .240 with 22 doubles, 13 home runs and 65 walks.
  • Among all MLB hitters, McCutchen ranks 156th in home runs and 133rd in RBI.
  • Oneil Cruz has a team-high 19 home runs.
  • Spencer Horwitz has 23 doubles, nine home runs and 39 walks while hitting .259.

Pirates pitching rankings

  • The 8.2 strikeouts per nine innings compiled by the Pirates pitching staff ranks 21st in MLB.
  • The Pirates’ 3.85 team ERA ranks eighth across all league pitching staffs.
  • Pirates pitchers combine for the No. 5 WHIP in baseball (1.223).
  • Pirates pitchers combine to allow the third-fewest home runs in baseball (147 total, 0.9 per game).
  • They struck out 13 Athletics batters while giving up one hit in a 2-0 win in their last game.

Athletics betting info, hitting leaders, & pitching

Athletics betting info

  • The Athletics have entered the game as underdogs 116 times this season and won 55, or 47.4%, of those games.
  • The Athletics have a record of 50-59, a 45.9% win rate, when they’re set as the underdog by -107 or more by oddsmakers this season.
  • The implied probability of a win by the Athletics, based on the moneyline, is 51.7%.
  • The Athletics and their opponents have hit the over in 73 of their 155 games with a total this season.
  • The Athletics are 82-73-0 against the spread in their 155 chances this season.

Athletics hitting info

  • Brent Rooker has been key for Sacramento with 30 home runs, 87 RBI and a batting average of .264 this season.
  • Rooker ranks 19th in homers and 30th in RBI among all batters in the big leagues.
  • Tyler Soderstrom is a key run producer for Sacramento with a .276 average, 24 homers and 90 RBI.
  • Soderstrom currently is 49th in homers and 24th in RBI in the big leagues.
  • Nick Kurtz leads Sacramento in home runs with 33. He’s driven in 81 runs and is slugging .615.
  • Jacob Wilson leads Sacramento with a .318 batting average. He’s also hit 13 homers and has 59 RBI.

Athletics pitching rankings

  • The Athletics have an 8.3 K/9 this season as a pitching staff, which ranks 20th in the big leagues.
  • The Athletics have pitched to a 4.68 ERA this season, which ranks 26th in baseball.
  • The Athletics have a combined WHIP of 1.360 as a pitching staff, which ranks 25th in MLB.
  • The Athletics have given up the second-most long balls so far this season with 215 home runs allowed.
  • Last time out, they fell to the Pirates, 2-0, with six strikeouts and five hits allowed.
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Betting Guide

How Money Line Works?

Moneyline betting is by far the easiest way to place a sports wager. There are no point spreads to parse, no garbage-time free throws to ruin your betting day, and no last-minute meaningless touchdowns to take you from a winner to a loser.

How to Bet Odds

When we, as sports fans, learned our multiplication tables, we aced the number 7. Seven, 14, 21, 28, 35, 42 were easy because we all watched football on the weekends. Multiplication by sevens, then add a three, a six after a missed PAT.

How to Bet on NFL Games

Baseball is America’s pastime, but football is America’s crazed passion, with its weekly schedule of games, millions of television viewers across the country and the world, and the billion-dollar stadiums that serve as Sunday cathedrals in 32 American cities.

What is the Spread?

If you are a golfer or have ever played on a bowling team, think of a point spread like a handicap. It is a way for two teams of differing abilities to play each other on equal footing.  The better team, and the favorite in the game, gives a certain amount …