Benfica is set to meet Real Madrid on Wednesday, Feb. 25 in the Champions League. The game at Santiago Bernabeu starts at 3 p.m. ET.

Check out all the Latest Betting Previews!

Real Madrid vs. Benfica Odds & Favorites

• Favorite: Real Madrid (-221)
• Underdog: Benfica (+490)
• Over/under: 3.5

Real Madrid vs. Benfica Betting Insights

• In LaLiga, Real Madrid has put up 75 goals in 38 matches (first in league), and Benfica has allowed 20 in 34 Primeira Liga matches (second).
• Real Madrid has been favored on the moneyline 36 times this LaLiga season, and has finished 24-6-6 in those games.
• Real Madrid has a 14-2-1 record (winning 82.4% of its LaLiga games) when it has played as a moneyline favorite of -221 or shorter.
• Based on this matchup’s moneyline, Real Madrid has an implied win probability of 68.8%.
• Offensively, Benfica is first in the Primeira Liga (82 goals, 2.4 per match). And defensively, Real Madrid is fourth in LaLiga (36 goals conceded, 0.9 per match).
• Benfica won the only Primeira Liga game it has played as an underdog this season.
• Benfica has not been a bigger underdog this season in the Primeira Liga than the +490 moneyline set for this game.
• The implied probability of a win by Benfica, based on the moneyline, is 16.9%.
• In 12 of 38 LaLiga matches this season, Real Madrid and its opponent have combined for more than 3.5 goals.
• Benfica has played 12 Primeira Liga games this season that ended with over 3.5 goals.

Real Madrid vs. Benfica Champions League Betting Insights

• In the Champions League, Real Madrid scores 2.4 goals per match and Benfica concedes 1.0.
• Thus far in Champions League play, Real Madrid has gone 6-0-1 in seven matches as a favorite.
• Real Madrid (-221) has been at least this big a favorite in four Champions League games, and won every time.
• Benfica scores 1.2 goals per match in Champions League play, and Real Madrid gives up 1.3.
• Benfica has been the underdog in five Champions League matches, and won once.
• Benfica has not been a +490 underdog or greater in Champions League play.
• In four games in Champions League action, Real Madrid and its opponent have combined to score more than 3.5 goals.
• Benfica Champions League games have finished with over 3.5 goals only two times.

Real Madrid vs. Benfica Offensive Leaders

Real Madrid Offensive Leaders

• Rodrygo has taken a team-high 59 shots (seventh in league) for Real Madrid in LaLiga, and scored nine goals.
• Real Madrid’s Vinicius Junior has taken 56 shots in LaLiga, and he has 10 goals.
• Real Madrid’s primary playmaker is Junior as well — he also leads the team with 58 chances created, and has nine assists.

Benfica Offensive Leaders

• Benfica’s Rafa Silva has 35 Primeira Liga shots (20th in league) and eight goals (12th) this season.
• In 28 Primeira Liga matches, Fredrik Aursnes has 17 shots and two goals.
• Silva also has five assists, and is tops on Benfica in chances created with (first in league, per game).