Saint Louis vs. Loyola Chicago betting: College basketball preview for March 4

Data Skrive

The No. 25 Saint Louis Billikens (26-3, 14-2 A-10) are heavily favored (by 22.5 points) to continue a 13-game home win streak when they host the Loyola Chicago Ramblers (7-22, 3-13 A-10) on Wednesday, March 4, 2026 at 8 p.m. ET. The point total is 155.5 in the matchup.

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Saint Louis Cover -22.5 vs Loyola Chicago -115

Bet $20, Payout $37.39

Saint Louis vs. Loyola Chicago betting lines

  • Saint Louis moneyline odds to win: -10000
  • Loyola Chicago moneyline odds to win: +2350
  • Spread: Saint Louis (-22.5)
  • Total: 155.5

Saint Louis statistics, trends and more

As the home team

  • Saint Louis sports a better record against the spread at home (13-4-0) than it does on the road (5-4-0).
  • The Billikens have eclipsed the over/under in 10 of 17 home games (58.8%), compared to five of nine road games (55.6%).
  • At home, Saint Louis has won more often as a moneyline favorite, producing a record of 17-0 (1.000). In away games, it is 6-2 (.750) as a moneyline favorite.

Recent trends

  • The Billikens’ offense has been worse over their last 10 games, scoring 85.4 points a contest compared to the 89.2 they’ve averaged this year.
  • The past 10 games have seen Saint Louis give up 3.0 more points per game (71.7) than its season-long average (68.7).
  • During their past 10 outings, the Billikens are making 1.3 more three-pointers per game than their season long average (12.6 compared to 11.3 season-long), while also shooting a higher percentage from beyond the arc in that span (45.7% compared to 40.9% season-long).

Saint Louis betting records this season

  • ATS Record: 18-10-0 (Home: 13-4-0; Away: 5-4-0)
  • ATS Record When Favored by 22.5+: 4-2-0 (As Favorite: 17-10-0; As Underdog: 1-0-0)
  • O-U-P: 15-13-0 (Home: 10-7-0; Away: 5-4-0)
  • Record When Moneyline Favorite: 24-3 (Home: 17-0; Away: 6-2)
  • Record When Moneyline Underdog: 1-0 (Home: 0-0; Away: 1-0)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
51.4 (fifth in nation) 36.9 (first) 37.8 (seventh) 29.0 (64th) 18.8 (sixth) 12.4 (308th)

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Loyola Chicago statistics, trends and more

As the away team

  • Against the spread, Loyola Chicago has an identical winning percentage (.333) at home (5-10-0 record) and on the road (3-6-0).
  • Ramblers games have gone above the over/under 46.7% of the time at home (seven of 15), and 55.6% of the time on the road (five of nine).
  • In 2025-26 as moneyline underdogs, the Ramblers have a better winning percentage at home (.143, 1-6 record) than on the road (.111, 1-8).

Recent trends

  • While the Ramblers are scoring 66.8 points per game in 2025-26, they have fallen short of that in their previous 10 games, tallying 65.1 points per contest.
  • Loyola Chicago has played better defensively over its previous 10 games, giving up 76.3 points per contest, 0.5 fewer points than its season average of 76.8 allowed.
  • The Ramblers are draining 8.1 treys per game with a 30.8% three-point percentage in their previous 10 games, compared to their season averages of 8.0 and 30.9%.

Loyola Chicago betting records this season

  • ATS Record: 9-20-0 (Home: 5-10-0; Away: 3-6-0)
  • O-U-P: 14-15-0 (Home: 7-8-0; Away: 5-4-0)
  • Record When Moneyline Favorite: 4-5 (Home: 4-4; Away: 0-0)
  • Record When Moneyline Underdog: 3-17 (Home: 1-6; Away: 1-8)
Field Goal % Opp. Field Goal % Rebounds Opp. Rebounds Assists Turnovers
41.9 (330th in nation) 44.1 (166th) 30.9 (242nd) 30.4 (143rd) 13.9 (171st) 12.5 (314th)
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