The No. 25 Saint Louis Billikens (26-3, 14-2 A-10) are heavily favored (by 22.5 points) to continue a 13-game home win streak when they host the Loyola Chicago Ramblers (7-22, 3-13 A-10) on Wednesday, March 4, 2026 at 8 p.m. ET. The point total is 155.5 in the matchup.
Check out all the Latest NCAA Basketball Betting Previews!
Saint Louis Cover -22.5 vs Loyola Chicago -115
Saint Louis vs. Loyola Chicago betting lines
- Saint Louis moneyline odds to win: -10000
- Loyola Chicago moneyline odds to win: +2350
- Spread: Saint Louis (-22.5)
- Total: 155.5
Saint Louis statistics, trends and more
As the home team
- Saint Louis sports a better record against the spread at home (13-4-0) than it does on the road (5-4-0).
- The Billikens have eclipsed the over/under in 10 of 17 home games (58.8%), compared to five of nine road games (55.6%).
- At home, Saint Louis has won more often as a moneyline favorite, producing a record of 17-0 (1.000). In away games, it is 6-2 (.750) as a moneyline favorite.
Recent trends
- The Billikens’ offense has been worse over their last 10 games, scoring 85.4 points a contest compared to the 89.2 they’ve averaged this year.
- The past 10 games have seen Saint Louis give up 3.0 more points per game (71.7) than its season-long average (68.7).
- During their past 10 outings, the Billikens are making 1.3 more three-pointers per game than their season long average (12.6 compared to 11.3 season-long), while also shooting a higher percentage from beyond the arc in that span (45.7% compared to 40.9% season-long).
Saint Louis betting records this season
- ATS Record: 18-10-0 (Home: 13-4-0; Away: 5-4-0)
- ATS Record When Favored by 22.5+: 4-2-0 (As Favorite: 17-10-0; As Underdog: 1-0-0)
- O-U-P: 15-13-0 (Home: 10-7-0; Away: 5-4-0)
- Record When Moneyline Favorite: 24-3 (Home: 17-0; Away: 6-2)
- Record When Moneyline Underdog: 1-0 (Home: 0-0; Away: 1-0)
| Field Goal % | Opp. Field Goal % | Rebounds | Opp. Rebounds | Assists | Turnovers |
|---|---|---|---|---|---|
| 51.4 (fifth in nation) | 36.9 (first) | 37.8 (seventh) | 29.0 (64th) | 18.8 (sixth) | 12.4 (308th) |
Need to know more about sports betting before you put down a wager on Saint Louis vs. Loyola Chicago? Here’s everything you need to know about how to bet.
Loyola Chicago statistics, trends and more
As the away team
- Against the spread, Loyola Chicago has an identical winning percentage (.333) at home (5-10-0 record) and on the road (3-6-0).
- Ramblers games have gone above the over/under 46.7% of the time at home (seven of 15), and 55.6% of the time on the road (five of nine).
- In 2025-26 as moneyline underdogs, the Ramblers have a better winning percentage at home (.143, 1-6 record) than on the road (.111, 1-8).
Recent trends
- While the Ramblers are scoring 66.8 points per game in 2025-26, they have fallen short of that in their previous 10 games, tallying 65.1 points per contest.
- Loyola Chicago has played better defensively over its previous 10 games, giving up 76.3 points per contest, 0.5 fewer points than its season average of 76.8 allowed.
- The Ramblers are draining 8.1 treys per game with a 30.8% three-point percentage in their previous 10 games, compared to their season averages of 8.0 and 30.9%.
Loyola Chicago betting records this season
- ATS Record: 9-20-0 (Home: 5-10-0; Away: 3-6-0)
- O-U-P: 14-15-0 (Home: 7-8-0; Away: 5-4-0)
- Record When Moneyline Favorite: 4-5 (Home: 4-4; Away: 0-0)
- Record When Moneyline Underdog: 3-17 (Home: 1-6; Away: 1-8)
| Field Goal % | Opp. Field Goal % | Rebounds | Opp. Rebounds | Assists | Turnovers |
|---|---|---|---|---|---|
| 41.9 (330th in nation) | 44.1 (166th) | 30.9 (242nd) | 30.4 (143rd) | 13.9 (171st) | 12.5 (314th) |

BetDecider Team
The BetDecider team brings you the most current sports betting content, with expert insights and tips. Our aim is that you can make an informed betting decision, including best odds and exclusive sportsbook offers, to maximize your betting experience.


