Padres vs. Diamondbacks Betting Lines, Odds, & Player Matchups September 26, 2025

Data Skrive
Data Skrive

Geraldo Perdomo sits at 98 RBI this season, and will try to collect his 100th when his Arizona Diamondbacks (80-79) play the San Diego Padres (87-72) on Friday at 9:40 p.m. ET. The Diamondbacks are the underdog (+125) in this matchup with the Padres (-151). Yu Darvish starts for San Diego while Arizona will counter with Zac Gallen.

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Moneyline

Padres to win vs Diamondbacks -151

Bet $20, Payout $33.25

Padres vs. Diamondbacks betting lines

  • Favorite: Padres (-151)
  • Underdog: Diamondbacks (+125)
  • Over/under: 7.5

Padres betting info, hitting leaders, & pitching

Padres betting info

  • The Padres have a 52-37 record in games they were listed as the moneyline favorite (winning 58.4% of those games).
  • San Diego has a 27-20 record (winning 57.4% of its games) when it has played as moneyline favorites of -151 or shorter.
  • Based on this matchup’s moneyline, the Padres have an implied win probability of 60.2%.
  • In the 159 games in which bookmakers have set an over/under for San Diego, it has combined with opponents to go over the total 67 times (67-86-6).
  • The Padres have gone 85-74-0 ATS this season.

Padres hitting info

  • Fernando Tatis Jr. is batting .267 with 27 doubles, two triples, 23 home runs and 88 walks.
  • Tatis’ home runs rank 58th in MLB and he ranks 97th in RBI in MLB.
  • Tatis takes a five-game hitting streak into this game. In his last five games he is hitting .381 with a home run, two walks and an RBI.
  • Manny Machado’s 26 home runs and 93 RBI are both team-highs.
  • Machado ranks 40th in homers and 22nd in RBI among batters in MLB action.
  • Luis Arraez has racked up a team-high batting average of .288.
  • Arraez heads into this game on a 13-game hitting streak. In his last 10 outings he is hitting .333 with a home run, four walks and six RBIs.
  • Ramon Laureano is batting .281 with 26 doubles, two triples, 24 home runs and 35 walks.

Padres pitching rankings

  • The Padres pitching staff ranks fifth in MLB with a collective 8.9 strikeouts per nine innings.
  • San Diego’s 3.65 team ERA ranks third across all MLB pitching staffs.
  • Pitchers for the Padres combine for the No. 3-ranked WHIP in the majors (1.204).
  • Padres pitchers combine to give up 174 total home runs at a clip of 1.1 per game (12th-fewest in baseball).
  • San Diego its 3-1 loss the last time out, the team struck out nine Brewers batters while allowing 10 hits.

Diamondbacks betting info, hitting leaders, & pitching

Diamondbacks betting info

  • This season, the Diamondbacks have won 34 out of the 69 games, or 49.3%, in which they’ve been the underdog.
  • Arizona has a record of 14-11, a 56% win rate, when it’s set as an underdog of +125 or more by sportsbooks this season.
  • The implied probability of a win by the Diamondbacks, based on the moneyline, is 44.4%.
  • Arizona’s games have gone over the total in 76 of its 158 chances.
  • In 158 games with a spread this season, the Diamondbacks are 82-76-0 ATS.

Diamondbacks hitting info

  • Perdomo is batting .289 with 98 RBI, both of which rank first among Arizona hitters this season.
  • Perdomo ranks 90th in homers and 14th in RBI among all batters in the majors.
  • Corbin Carroll’s 31 home runs are most among Arizona batters. He’s driven in 84 runs this season while slugging .544.
  • Carroll ranks 17th among batters in the big leagues in homers, and 38th in RBI.
  • Ketel Marte has collected 134 base hits, an OBP of .376 and a slugging percentage of .507 this season.
  • Marte has hit safely in six games in a row. During his last 10 outings he is batting .311 with six doubles, a home run and five RBIs.
  • Gabriel Moreno has collected 76 hits this season and has an OBP of .349. He’s slugging .437 on the year.

Diamondbacks pitching rankings

  • The Diamondbacks average the 23rd-most strikeouts per nine innings (8.0) in the majors this season.
  • Arizona has the 23rd-ranked ERA (4.44) in the majors this season.
  • Diamondbacks pitchers have a 1.313 WHIP this season, 21st in the majors.
  • The Diamondbacks have allowed the 18th-fewest home runs this season with 191, or 1.2 per game.
  • Arizona pitchers struck out 10 Dodgers hitters while allowing 11 base hits in an 8-0 loss its last time out.
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